Manning, Janet R; Perkins, Sarah O; Sinclair, Elizabeth A; Gao, Xiaoqian; Zhang, Yu; Newman, Gilbert; Pyle, W Glen; Schultz, Jo El J 2013. Low molecular weight fibroblast growth factor-2 signals via protein kinase C and myofibrillar proteins to protect against postischemic cardiac dysfunction. American journal of physiology. Heart and circulatory physiology, 304 10, H1382-96
Wijeratne, Aruna B; Manning, Janet R; Schultz, Jo El J; Greis, Kenneth D 2013. Quantitative phosphoproteomics using acetone-based Peptide labeling: method evaluation and application to a cardiac ischemia/reperfusion model. Journal of proteome research, 12 10, 4268-79
Bolte, Craig; Zhang, Yufang; York, Allen; Kalin, Tanya V; Schultz, Jo El J; Molkentin, Jeffery D; Kalinichenko, Vladimir V 2012. Postnatal ablation of Foxm1 from cardiomyocytes causes late onset cardiac hypertrophy and fibrosis without exacerbating pressure overload-induced cardiac remodeling. PloS one, 7 11, e48713
Manning, Janet R; Carpenter, Gregory; Porter, Darius R; House, Stacey L; Pietras, Daniel A; Doetschman, Thomas; Schultz, Jo el J 2012. Fibroblast growth factor-2-induced cardioprotection against myocardial infarction occurs via the interplay between nitric oxide, protein kinase signaling, and ATP-sensitive potassium channels. Growth factors (Chur, Switzerland), 30 2, 124-39
Schulz, Emily M; Correll, Richard N; Sheikh, Hajer N; Lofrano-Alves, Marco S; Engel, Patti L; Newman, Gilbert; Schultz, Jo El J; Molkentin, Jeffery D; Wolska, Beata M; Solaro, R John; Wieczorek, David F 2012. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy. The Journal of biological chemistry, 287 53, 44478-89
House, Stacey L; House, Brian E; Glascock, Betty; Kimball, Thomas; Nusayr, Eyad; Schultz, Jo El J; Doetschman, Thomas 2010. Fibroblast Growth Factor 2 Mediates Isoproterenol-induced Cardiac Hypertrophy through Activation of the Extracellular Regulated Kinase. Molecular and cellular pharmacology, 2 4, 143-154
Liao, Siyun; Bodmer, Janet R; Azhar, Mohamad; Newman, Gilbert; Coffin, J Douglas; Doetschman, Thomas; Schultz, Jo El J 2010. The influence of FGF2 high molecular weight (HMW) isoforms in the development of cardiac ischemia-reperfusion injury. Journal of molecular and cellular cardiology, 48 6, 1245-54
Bolte, Craig; Newman, Gilbert; Schultz, Jo El J 2009. Kappa and delta opioid receptor signaling is augmented in the failing heart. Journal of molecular and cellular cardiology, 47 4, 493-503
Bolte, Craig; Newman, Gilbert; Schultz, Jo El J 2009. Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac kappa-opioid receptor stimulation. American journal of physiology. Heart and circulatory physiology, 296 4, H967-75
Jones, W Keith; Fan, Guo-Chang; Liao, Siyun; Zhang, Jun-Ming; Wang, Yang; Weintraub, Neal L; Kranias, Evangelia G; Schultz, Jo El; Lorenz, John; Ren, Xiaoping 2009. Peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling. Circulation, 120 11 Suppl, S1-9
Flaherty M, Brown M, Grupp I, Schultz J, Murphree S, Jones WK 2007. eNOS deficient mice develop progressive cardiac hypertrophy with altered cytokine and calcium handling protein expression Cardiovasc Tox, 7 3, 165-77
House SL, Melhorn S, Newman G, Doetschman T, Schultz Jel J 2007. Cardiac-specific overexpression of FGF2 is cardioprotective via a protein kinase C-dependent pathway in a murine model of global low-flow ischemia Am J Physiol, 293 1, H354-65
Liao, Siyun; Porter, Darius; Scott, Alana; Newman, Gilbert; Doetschman, Thomas; Schultz, Jo El J 2007. The cardioprotective effect of the low molecular weight isoform of fibroblast growth factor-2: the role of JNK signaling. Journal of molecular and cellular cardiology, 42 1, 106-20
Ji Y, Zhao W, Kaetzel M, Li B, Schultz Jel J, Kranias E, Bers DM, Dedman JR 2006. Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility Am J Physiol, 290 2, H599-606
Ji, Yong; Zhao, Wen; Li, Bailing; Desantiago, Jaime; Picht, Eckard; Kaetzel, Marcia A; Schultz, Jo El J; Kranias, Evangelia G; Bers, Donald M; Dedman, John R 2006. Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility. American journal of physiology. Heart and circulatory physiology, 290 2, H599-606
Zhao W, Yuan Q, Pathak A, Chu G, Mitton B, Waggoner J, Qian J, Sun X, Jin J, Braz JC, Hahn HS, Marreez Y, Syed F, Pollesello P, Annila A, Brown KM, Wang H, Schultz Jel J, Molkentin JG, Liggett SB, Dorn II GW, Kranias EG 2006. The presence of Lys27 instead of Asn27 in human phospholamban promotes SERCA2 superinhibition and cardiac remodeling Circulation, 113 7, 995-1004
Zhao, Wen; Yuan, Qunying; Qian, Jiang; Waggoner, Jason R; Pathak, Anand; Chu, Guoxiang; Mitton, Bryan; Sun, Xiaoyin; Jin, Jay; Braz, Julian C; Hahn, Harvey S; Marreez, Yehia; Syed, Faisal; Pollesello, Piero; Annila, Arto; Wang, Hong-Sheng; Schultz, Jo El J; Molkentin, Jeffery D; Liggett, Stephen B; Dorn, Gerald W; Kranias, Evangelia G 2006. The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling. Circulation, 113 7, 995-1004
Gumina RJ, El Schultz J, Moore J, Beier N, Schelling P, Gross GJ 2005. Cardioprotective-mimetics reduce myocardial infarct size in animals resistant to ischemic preconditioning Cardiovasc Drugs Ther, 19 5, 315-22
House SL, Branch K, Newman G, Doetschman T, Schultz Jel J 2005. Cardioprotection induced by cardiac-specific overexpression of fibroblast growth factor-2 is mediated by the MAPK cascade Am J Physiol, 289 5, H2167-2175
Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, Mavila N, Jha L, Qian J, Mareez Y, Chen G, McGraw DW, Heist EK, Guerrero JL, DePaoli-Roach AA, Hajjar RJ, Kranias EG 2005. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1 Circ Res, 96 7, 756-766
Dostanic I, Schultz Jel J, Lorenz JN, Lingrel JB 2004. The 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca-exchanger in heart J Biol Chem, 279 52, 54053-54061
Dostanic, Iva; Schultz, Jo El J; Lorenz, John N; Lingrel, Jerry B 2004. The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart. The Journal of biological chemistry, 279 52, 54053-61
Moseley AE, Cougnon MH, Grupp IL, El Schultz J, Lingrel JB 2004. Attenuation of cardiac contractility in Na,K-ATPase 1 isoform-deficient hearts under reduced calcium conditions J Mol Cell Cardiol, 37 5, 913-919
Schultz Jel J, Glascock BJ, Witt SA, Nieman ML, Nattami KJ, Liu LH, Lorenz JN, Shull GE, Kimball TR, Periasamy M 2004. Accelerated onset of heart failure during pressure overload in mice with chronically decreased SERCA2 calcium pump activity Am J Physiol, 286 , H1146-1153
Schultz, Jo El J; Glascock, Betty J; Witt, Sandra A; Nieman, Michelle L; Nattamai, Kalpana J; Liu, Lynne H; Lorenz, John N; Shull, Gary E; Kimball, Thomas R; Periasamy, Muthu 2004. Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity. American journal of physiology. Heart and circulatory physiology, 286 3, H1146-53
Azhar, Mohamad; Schultz, Jo El J; Grupp, Ingrid; Dorn, Gerald W; Meneton, Pierre; Molin, Daniel G M; Gittenberger-de Groot, Adriana C; Doetschman, Thomas 2003. Transforming growth factor beta in cardiovascular development and function. Cytokine & growth factor reviews, 14 5, 391-407
Dostanic I, Lorenz JN, Schultz Jel J, Grupp IL, Neumann JC, Lingrel JB 2003. Increase in cardiac contractility by low concentrations of ouabain is mediated through the 2 NA,K-ATPase isozyme J Biol Chem, 278 52, 53026-53034
Dostanic, Iva; Lorenz, John N; Schultz, Jo El J; Grupp, Ingrid L; Neumann, Jonathan C; Wani, Maqsood A; Lingrel, Jerry B 2003. The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in mice. The Journal of biological chemistry, 278 52, 53026-34
House SL, Bolte C, Zhou M, Doetschman T, Klevitsky R, Newman G, Schultz Jel J 2003. Cardiac-specific overexpression of fibroblast growth factor-2 (FGF2) protects against myocardial dysfunction and infarction in a murine model of low-flow ischemia Circulation, 108 , 3140-3148
Maslov LN, Lishmanov YB, Gross GJ, Schultz JE, Stefano G 2002. Opioid receptor activation alters cardiac tolerance to ischemic and reperfusion damages Vestnik Arrhythmologyi (Russian), N28 , 67-78
Schultz Jel J, Witt SA, Glascock BJ, Nieman ML, Reiser PJ, Nix S, Kimball TR, Doetschman T 2002. Transforming growth factor-1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II (see commentary: Schneider MD. Serial killer: angiotensin drives cardiac hypertrophy via TGF-1 J Clin Invest, 109 , 715-716
Schultz, Jo El J; Witt, Sandra A; Glascock, Betty J; Nieman, Michelle L; Reiser, Peter J; Nix, Stacey L; Kimball, Thomas R; Doetschman, Thomas 2002. TGF-beta1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II. The Journal of clinical investigation, 109 6, 787-96
Fryer R, Schultz JE, Hsu A, Gross G 1999. Importance of PKC and tyrosine kinase in single or multiple cycles of preconditioning in rat hearts Am J Physiol, 276 , H1229-H1235
Schultz JE, Witt SA, Nieman ML, Reiser PJ, Engle SJ, Zhou M, Pawlowski SA, Lorenz JN, Kimball TR, Doetschman T 1999. Fibroblast growth factor-2 mediates pressure-induced hypertrophic response (featured on cover) J Clin Invest, 104 , 709-719
Schultz, J E; Witt, S A; Nieman, M L; Reiser, P J; Engle, S J; Zhou, M; Pawlowski, S A; Lorenz, J N; Kimball, T R; Doetschman, T 1999. Fibroblast growth factor-2 mediates pressure-induced hypertrophic response. The Journal of clinical investigation, 104 6, 709-19
Fryer RM, Schultz JE, Hsu AK, Gross GJ 1998. Pretreatment with tyrosine kinase inhibitors partially attenuates ischemic preconditioning in the rat heart Am J Physiol, 275 , H2009-H2015
Gumina RJ, Mizumura T, Beier N, Schelling P, Schultz JJ, Gross GJ 1998. A new sodium/hydrogen exchanger inhibitor, EMD 85131, limits infarct size in dogs when administered before or after coronary artery occlusion J Pharmacol Exp Therap, 286 1, 175-183
Schultz J el-J, Hsu AK, Nagase H, Gross GJ 1998. TAN-67, a selective delta-1 (1) opioid receptor agonist, reduces myocardial infarct size via activation of Gi/o proteins and KATP channels Am J Physiol, 274 , H909-H914
Schultz JE, Hsu AK, Barbieri JT, Li P-L, Gross GJ 1998. Pertussis toxin abolishes the cardioprotective effect of ischemic preconditioning in the intact rat heart Am J Physiol, 275 , H495-H500
Schultz JE, Hsu AK, Gross GJ 1998. Ischemic preconditioning (PC) in the intact rat heart is mediated by delta1 (1), but not mu () or kappa () opioid receptors Circulation, 97 , 1282-1289
Schultz JE, Hsu AK, Kwok W-M, Gross GJ 1998. Terikalant, the inward-rectifier potassium channel blocker, does not abolish the cardioprotection induced by ischemic preconditioning in the rat J Mol Cell Cardiol, 30 , 1817-1825
Schultz JE, Qian YZ, Gross GJ, Kukreja RC 1997. The ischemia-selective KATP channel antagonist, 5-hydroxydecanoate, blocks the ischemic preconditioning in the rat heart J Mol Cell Cardiol, 29 , 1055-1060
Schultz JE, Yao Z, Cavero I, Gross GJ 1997. Glibenclamide abolishes ischemic preconditioning in a time-dependent manner in the rat heart Am J Physiol, 272 , H2607-H2615
Schultz JJ, Hsu AK, Gross GJ 1997. Ischemic preconditioning is mediated by a peripheral opioid receptor mechanism in the intact rat heart J Mol Cell Cardiol, 29 , 1355-1362
Schultz JJ, Hsu AK, Gross GJ 1997. Ischemic preconditioning and morphine-induced cardioprotection involve the delta ()-opioid receptor in the intact rat heart J Mol Cell Cardiol, 29 , 2187-2195
Smart SC, Sagar KB, el Schultz J, Warltier DC, Jones LR 1997. Injury to the Ca2+ ATPase of the sarcoplasmic reticulum in anesthetized dogs contributes to myocardial reperfusion injury Cardiovasc Res, 36 , 174-184
Gumina RJ, el Schultz J, Yao Z, Kenny D, Warltier DC, Newman PJ, Gross GJ 1996. Antibody to Platelet/Endothelial Cell Adhesion Molecule-1 reduces myocardial infarct size in a rat model of ischemia/reperfusion injury Circulation, 94 , 3327-3333
Schultz JE, Hsu AK, Gross GJ 1996. Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart Circ Res, 78 , 1100-1104
Schultz JE, Rose E, Yao Z, Gross GJ 1995. Evidence for the involvement of opioid receptors in ischemic preconditioning in the rat heart Am J Physiol, 268 , H2157-H2161
Smart SC, LoCurto A, el Schultz J, Sagar KB, Warltier DC 1995. Intracoronary amiloride prevents contractile dysfunction of postischemic “stunned” myocardium: role of hemodynamic alterations and inhibition of Na+/H+ exchange and L-type Ca2+ channels J Am Coll Cardiol, 26 5, 1365-1373