Education/CredentialsMasters of Science: Duke University (Clinical Research)Residency: University of Cincinnati (Emergency Medicine)MD: University of CincinnatiBachelor of Science: Xavier University (Biology) Board Certifications & LicensesAmerican Board of Emergency Medicine (Certification Date: 2011-06-08) - (Recertification Date: 2022-01-01) SpecialtiesEmergency Medicine Contact Information Medical Sciences Building Email eadyce@ucmail.uc.edu Research InterestsEmergency Medicine Clinical Interests Emergency MedicineSickle Cell AnemiaPainSubstance Use Disorder Peer Reviewed Publications Brown, Jennifer L; Larochelle, Marc R; Fanucchi, Laura C; Calvert, Deirdre C; Campbell, Aimee N C; Chandler, Redonna K; Feaster, Daniel J; Glasgow, LaShawn M; Gibson, Erin B; Holloway, JaNae; Lofwall, Michelle R; Mack, Aimee; Mack, Nicole; Nunes, Edward V; Talbert, Jeffery C; Tan, Sylvia; Vandergrift, Nathan; Villani, Jennifer; Asman, Kat; Babakhanlou-Chase, Hermik; Bagley, Sarah M; Battaglia, Tracy A; Blevins, Derek; Bridden, Carly; Cheng, Debbie M; Christopher, Mia; Cogan, Lindsay W; Cunningham, Chinazo O; Eggleston, Barry; Fareed, Naleef; Fernandez, Soledad; Freedman, Darcy A; Freiermuth, Caroline E; Freisthler, Bridget; Gilbert, Louisa; Hammerslag, Lindsey; Harris, Daniel; Hunt, Timothy; Hussain, Shazia; Huynh, Phuong; Jackson, Rebecca D; Kauffman, Emily B; Knott, Charles; Knudsen, Hannah K; Lefebvre, R Craig; Levin, Frances R; Massatti, Rick; McAlearney, Ann Scheck; Morgan, Jake R; Lopez, Rosie Munoz; Lounsbury, David W; Newman, Lisa; Nickels, Katrina; Oga, Emmanuel A; Oller, Devin A; Parran, Theodore V; Quinn, Maria; Ramsey, Kelly S; Rapkin, Bruce D; Salsberry, Pamela; Stein, Michael; Taylor, Jessica L; Teater, Julie; Walters, Scott T; Zarkin, Gary A; El-Bassel, Nabila; Winhusen, T John; Samet, Jeffrey H; Walsh, Sharon L 2025. Effects of the Communities That HEAL intervention on initiation, retention, and linkage to medications for opioid use disorder (MOUD): A cluster randomized wait-list controlled trial. Drug and alcohol dependence, 274 , 112785Ibemere, Stephanie O; Barnhart, Huiman; Myers, John; Miller, Joseph; Osunkwo, Ifeyinwa; Bosworth, Hayden B; Freiermuth, Caroline E; Hughes, Robert; Kavanagh, Patricia L; Paice, Judith A; Paxton, James; Pierce, Ava; Runyon, Michael S; Strouse, John J; Veeramreddy, Padmaja; Wilkerson, R Gentry; Tanabe, Paula 2025. Impact of Individualized Versus Weight-Based Pain Protocols on Patient Satisfaction for Patients With Sickle Cell Disease Experiencing a Vaso-Occlusive Episode. Journal of emergency nursing, 51 4, 626-635McMonagle, Brianna N; Braun, Robert; Luke, Jude; Goel, Anita; Freiermuth, Caroline 2025. Patient Acceptance of Rapid HIV Testing During Targeted Screening in the Emergency Department. The western journal of emergency medicine, 26 4, 1124-1126Petrovitch, Dan; Himes, Katie P; Bischof, Jason J; Braun, Robert S; Brown, Jennifer L; Eleda, Isaiah C; Freiermuth, Caroline E; Gu, Shaopeng; Hall, O Trent; Johnson, Julie A; Kisor, David F; Lambert, Joshua W; Lyons, Michael S; Maloney, Morgan V; Punches, Brittany E; Quarles, Emma; Littlefield, Andrew K; Sprague, Jon E 2025. Scoping review of associations between cytochrome P450 3A4/5 single nucleotide polymorphisms and risk factors for fentanyl overdose. Pharmacogenomics, , 1-35Petrovitch, Dan; Himes, Katie P; Quarles, Emma; Freiermuth, Caroline E; Braun, Robert S; Lambert, Joshua W; Brown, Jennifer L; Lyons, Michael S; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2025. Negative urgency accounts for associations between internalizing symptoms and lifetime nonfatal opioid overdose among patients from three urban Ohio emergency departments. Experimental and clinical psychopharmacology, 33 3, 300-309Sabedra, Alexa; Freiermuth, Caroline; Santen, Sally; Leenellett, Elizabeth 2025. Faculty development committee: Evolution through engagement and empowerment. AEM education and training, 9 Suppl 1, S66-S72, ; Samet, Jeffrey H; El-Bassel, Nabila; Winhusen, T John; Jackson, Rebecca D; Oga, Emmanuel A; Chandler, Redonna K; Villani, Jennifer; Freisthler, Bridget; Adams, Joella; Aldridge, Arnie; Angerame, Angelo; Babineau, Denise C; Bagley, Sarah M; Baker, Trevor J; Balvanz, Peter; Barbosa, Carolina; Barocas, Joshua; Battaglia, Tracy A; Beard, Dacia D; Beers, Donna; Blevins, Derek; Bove, Nicholas; Bridden, Carly; Brown, Jennifer L; Bush, Heather M; Bush, Joshua L; Caldwell, Ryan; Calver, Katherine; Calvert, Deirdre; Campbell, Aimee N C; Carpenter, Jane; Caspar, Rachel; Chassler, Deborah; Chaya, Joan; Cheng, Debbie M; Cunningham, Chinazo O; Dasgupta, Anindita; David, James L; Davis, Alissa; Dean, Tammy; Drainoni, Mari-Lynn; Eggleston, Barry; Fanucchi, Laura C; Feaster, Daniel J; Fernandez, Soledad; Figueroa, Wilson; Freedman, Darcy A; Freeman, Patricia R; Freiermuth, Caroline E; Friedlander, Eric; Gelberg, Kitty H; Gibson, Erin B; Gilbert, Louisa; Glasgow, LaShawn; Goddard-Eckrich, Dawn A; Gomori, Stephen; Gruss, Dawn E; Gulley, Jennifer; Gutnick, Damara; Hall, Megan E; Harger Dykes, Nicole; Hargrove, Sarah L; Harlow, Kristin; Harris, Aumani; Harris, Daniel; Helme, Donald W; Holloway, JaNae; Hotchkiss, Juanita; Huang, Terry; Huerta, Timothy R; Hunt, Timothy; Hyder, Ayaz; Ingram, Van L; Ingram, Tim; Kauffman, Emily; Kimball, Jennifer L; Kinnard, Elizabeth N; Knott, Charles; Knudsen, Hannah K; Konstan, Michael W; Kosakowski, Sarah; Larochelle, Marc R; Leaver, Hannah M; LeBaron, Patricia A; Lefebvre, R Craig; Levin, Frances R; Lewis, Nikki; Lewis, Nicky; Lofwall, Michelle R; Lounsbury, David W; Luster, Jamie E; Lyons, Michael S; Mack, Aimee; Marks, Katherine R; Marquesano, Stephanie; Mauk, Rachel; McAlearney, Ann Scheck; McConnell, Kristin; McGladrey, Margaret L; McMullan, Jason; Miles, Jennifer; Munoz Lopez, Rosie; Nelson, Alisha; Neufeld, Jessica L; Newman, Lisa; Nguyen, Trang Q; Nunes, Edward V; Oller, Devin A; Oser, Carrie B; Oyler, Douglas R; Pagnano, Sharon; Parran, Theodore V; Powell, Joshua; Powers, Kim; Ralston, William; Ramsey, Kelly; Rapkin, Bruce D; Reynolds, Jennifer G; Roberts, Monica F; Robertson, Will; Rock, Peter; Rodgers, Emma; Rodriguez, Sandra; Rudorf, Maria; Ryan, Shawn; Salsberry, Pamela; Salvage, Monika; Sabounchi, Nasim; Saucier, Merielle; Savitzky, Caroline; Schackman, Bruce; Schady, Elizabeth; Seiber, Eric E; Shadwick, Aimee; Shoben, Abigail; Slater, Michael D; Slavova, Svetla; Speer, Drew; Sprunger, Joel; Starbird, Laura E; Staton, Michele; Stein, Michael D; Stevens-Watkins, Danelle J; Stopka, Thomas J; Sullivan, Ann; Surratt, Hilary L; Sword Cruz, Rachel; Talbert, Jeffery C; Taylor, Jessica L; Thompson, Katherine L; Vandergrift, Nathan; Vickers-Smith, Rachel A; Vietze, Deanna J; Walker, Daniel M; Walley, Alexander Y; Walters, Scott T; Weiss, Roger; Westgate, Philip M; Wu, Elwin; Young, April M; Zarkin, Gary A; Walsh, Sharon L 2024. Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths. The New England journal of medicine, 391 11, 989-1001Freiermuth, Caroline E; Foster, Jenny A; Manandhar, Pratik; Arulraja, Evangeline; Erkanli, Alaattin; Pollack, Charles V; Eucker, Stephanie A 2024. Opioid Treatment Is Associated with Recurrent Healthcare Visits, Increased Side Effects, and Pain. The western journal of emergency medicine, 25 6, 875-882Himes, Katie P; Dan Petrovitch, M A; Freiermuth, Caroline E; Bachmann, Daniel J; Bischof, Jason J; Braun, Robert S; Brown, Jennifer L; Frey, Jennifer A; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2024. Are opioid use disorder assessments in the emergency department biased? An examination across sex, race, and employment status using item response theory. General hospital psychiatry, 91 , 186-189Lambert, Joshua; Petrovitch, Dan; Himes, Katie P; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Bischof, Jason J; Lyons, Michael S; Punches, Brittany E; Littlefield, Andrew K; Kisor, David F; Sprague, Jon E 2024. Association of genetic variants in CYP3A5, DRD2 and NK1R with opioid overdose. Chemico-biological interactions, 403 , 111242Littlefield, Andrew K; Himes, Katie P; Petrovitch, Dan; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Bischof, Jason J; Punches, Brittany E; Sprague, Jon E 2024. The relations between impulsivity, opioid use, and nonmedical prescription opioid use motives: An examination within three large urban emergency departments. Experimental and clinical psychopharmacology, 32 6, 652-663Petrovitch, Dan; Himes, Katie P; Jump, Alayna; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Lyons, Michael S; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2024. State program enables the identification of factors associated with naloxone awareness, self-efficacy, and use for overdose reversal: A cross-sectional, observational study in an urban emergency department population. Journal of substance use and addiction treatment, 167 , 209506Punches, Brittany E; Freiermuth, Caroline E; Sprague, Jon E; Brown, Jennifer L; Hutzel-Dunham, Elizabeth; Lambert, Joshua; Braun, Robert; Littlefield, Andrew; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Pantalon, Michael V; Ancona, Rachel M; Kisor, David F; Lyons, Michael S 2024. Screening for problematic opioid use in the emergency department: Comparison of two screening measures. Journal of the American College of Emergency Physicians open, 5 1, e13106Sprague, Jon E; Freiermuth, Caroline E; Lambert, Joshua; Braun, Robert; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Beaumont, Lauren; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Ancona, Rachel; Kisor, David F 2024. Opioid use disorder risk alleles in self-reported assigned African American/Afro-Caribbean and European biogeographical genetic ancestry groups and in males and females. The pharmacogenomics journal, 24 4, 23D'Onofrio, Gail; Edelman, E Jennifer; Hawk, Kathryn F; Chawarski, Marek C; Pantalon, Michael V; Owens, Patricia H; Martel, Shara H; Rothman, Richard; Saheed, Mustapha; Schwartz, Robert P; Cowan, Ethan; Richardson, Lynne; Salsitz, Edwin; Lyons, Michael S; Freiermuth, Caroline; Wilder, Christine; Whiteside, Lauren; Tsui, Judith I; Klein, Jared W; Coupet, Edouard; O'Connor, Patrick G; Matthews, Abigail G; Murphy, Sean M; Huntley, Kristen; Fiellin, David A 2023. Implementation Facilitation to Promote Emergency Department-Initiated Buprenorphine for Opioid Use Disorder. JAMA network open, 6 4, e235439Freiermuth, Caroline E; Ancona, Rachel M; Brown, Jennifer L; Punches, Brittany E; Ryan, Shawn A; Ingram, Tim; Lyons, Michael S 2023. Evaluation of a large-scale health department naloxone distribution program: Per capita naloxone distribution and overdose morality. PloS one, 18 8, e0289959Freiermuth, Caroline E; Kisor, David F; Lambert, Joshua; Braun, Robert; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Ancona, Rachel; Sprague, Jon E 2023. Genetic Variants Associated With Opioid Use Disorder. Clinical pharmacology and therapeutics, 113 5, 1089-1095Tanabe, Paula; Ibemere, Stephanie; Pierce, Ava E; Freiermuth, Caroline E; Bosworth, Hayden B; Yang, Hongqui; Osunkwo, Ifeyinwa; Paxton, James H; Strouse, John J; Miller, Joseph; Paice, Judith A; Veeramreddy, Padmaja; Kavanagh, Patricia L; Wilkerson, R Gentry; Hughes, Robert; Barnhart, Huiman X 2023. A comparison of the effect of patient-specific versus weight-based protocols to treat vaso-occlusive episodes in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 30 12, 1210-1222Bellolio, Fernanda; Broder, Joshua S; Oliveira J E Silva, Lucas; Freiermuth, Caroline E; Hooker, Edmond; Jang, Timothy B; Griffey, Richard T; Meltzer, Andrew C; Mills, Angela M; Pepper, Joan; Prakken, Steven; Repplinger, Michael D; Upadhye, Suneel; Carpenter, Christopher R 2022. Reply to "Letter to the Editor, re: GRACE-2: Low-Risk, Recurrent Abdominal Pain in the Emergency Department". Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 29 9, 1148-1150Broder, Joshua S; Oliveira J E Silva, Lucas; Bellolio, Fernanda; Freiermuth, Caroline E; Griffey, Richard T; Hooker, Edmond; Jang, Timothy B; Meltzer, Andrew C; Mills, Angela M; Pepper, Joan D; Prakken, Steven D; Repplinger, Michael D; Upadhye, Suneel; Carpenter, Christopher R 2022. Guidelines for Reasonable and Appropriate Care in the Emergency Department 2 (GRACE-2): Low-risk, recurrent abdominal pain in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 29 5, 526-560Faryar, Kiran A; Braun, Robert; Ancona, Rachel M; Freiermuth, Caroline; Lyons, Michael S 2022. Acceptance of HIV pre-exposure prophylaxis (PrEP) referral among a sample of PrEP-eligible emergency department patients. The American journal of emergency medicine, 60 , 152-155Ojeda, Myriam Shaw; Chen, Aleda M H; Miracle, Tessa; Delaney, Elizabeth; Freiermuth, Caroline E; Sprague, Jon E 2022. HealthCare educational differences in pain management, adverse childhood experiences and their relationship to substance use disorder education. Substance abuse treatment, prevention, and policy, 17 1, 10Punches, Brittany E; Brown, Jennifer L; Soliman, Summer; Johnson, Kimberly D; Freiermuth, Caroline E; Walker, Quinn; Omololu, Shammah O; Lyons, Michael S 2022. Patient Pain Experiences and the Emergency Department Encounter: A Qualitative Analysis. Pain management nursing : official journal of the American Society of Pain Management Nurses, 23 4, 391-396Punches, Brittany E; Stolz, Uwe; Freiermuth, Caroline E; Ancona, Rachel M; McLean, Samuel A; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Zeng, Donglin; Neylan, Thomas C; Clifford, Gari D; Jovanovic, Tanja; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Kurz, Michael C; Gentile, Nina T; McGrath, Meghan E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Chang, Anna M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Pietrzak, Robert H; Joormann, Jutta; Barch, Deanna M; Pizzagalli, Diego A; Smoller, Jordan W; Luna, Beatriz; Harte, Steven E; Elliott, James M; Kessler, Ronald C; Ressler, Kerry J; Koenen, Karestan C; Lyons, Michael S 2022. Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study. PloS one, 17 9, e0273378Westafer, Lauren M; Freiermuth, Caroline E; Lall, Michelle D; Muder, Sarah J; Ragone, Eleanor L; Jarman, Angela F 2022. Experiences of Transgender and Gender Expansive Physicians. JAMA network open, 5 6, e2219791Whiteside, Lauren K; D'Onofrio, Gail; Fiellin, David A; Edelman, E Jennifer; Richardson, Lynne; O'Connor, Patrick; Rothman, Richard E; Cowan, Ethan; Lyons, Michael S; Fockele, Callan E; Saheed, Mustapha; Freiermuth, Caroline; Punches, Brittany E; Guo, Clara; Martel, Shara; Owens, Patricia H; Coupet, Edouard; Hawk, Kathryn F 2022. Models for Implementing Emergency Department-Initiated Buprenorphine With Referral for Ongoing Medication Treatment at Emergency Department Discharge in Diverse Academic Centers. Annals of emergency medicine, 80 5, 410-419Eucker, Stephanie A; Manandhar, Pratik; Arulraja, Kami; Agnihotri, Deepti; Pollack, Charles V; Freiermuth, Caroline 2021. Higher daily pain severity after emergency department visits is associated with lower return-to-work rates. The American journal of emergency medicine, 45 , 48-53Ibemere, Stephanie O; Dubbs, Sarah B; Barnhart, Huiman X; Brown, Jacqueline L; Freiermuth, Caroline E; Kavanagh, Patricia; Paice, Judith A; Strouse, John J; Wilkerson, R Gentry; Tanabe, Paula 2021. Trial design of comparing patient-specific versus weight-based protocols to treat vaso-occlusive episodes in sickle cell disease (COMPARE-VOE). Contemporary clinical trials, 101 , 106252Lane, Bennett H; Lyons, Michael S; Stolz, Uwe; Ancona, Rachel M; Ryan, Richard J; Freiermuth, Caroline E 2021. Naloxone provision to emergency department patients recognized as high-risk for opioid use disorder. The American journal of emergency medicine, 40 , 173-176McCorkle, Maggie L; Kisor, David F; Freiermuth, Caroline E; Sprague, Jon E 2021. Systematic review of Pharmacogenomics Knowledgebase evidence for pharmacogenomic links to the dopamine reward pathway for heroin dependence. Pharmacogenomics, 22 13, 849-857Punches, Brittany E; Ancona, Rachel M; Freiermuth, Caroline E; Brown, Jennifer L; Lyons, Michael S 2021. Incidence of opioid use disorder in the year after discharge from an emergency department encounter. Journal of the American College of Emergency Physicians open, 2 3, e12476Punches, Brittany E; Berger, Kimberly M; Freiermuth, Caroline E; Soliman, Summer A; Walker, Quinn T; Lyons, Michael S 2021. Emergency Nurse Perceptions of Pain and Opioids in the Emergency Department. Pain management nursing : official journal of the American Society of Pain Management Nurses, 22 5, 586-591Punches, Brittany E; Soliman, Summer; Freiermuth, Caroline E; Lane, Bennett H; Lyons, Michael S 2020. Emergency Nurse Perceptions of Naloxone Distribution in the Emergency Department. Journal of emergency nursing, 46 5, 675-681.e1Freiermuth, Caroline E; Lavonas, Eric J; Anderson, Victoria E; Kleinschmidt, Kurt C; Sharma, Kapil; Rapp-Olsson, Malin; Gerardo, Charles 2019. Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation. The western journal of emergency medicine, 20 3, 497-505Fulton, Jessica J; LeBlanc, Thomas W; Cutson, Toni M; Porter Starr, Kathryn N; Kamal, Arif; Ramos, Katherine; Freiermuth, Caroline E; McDuffie, Jennifer R; Kosinski, Andrzej; Adam, Soheir; Nagi, Avishek; Williams, John W 2019. Integrated outpatient palliative care for patients with advanced cancer: A systematic review and meta-analysis. Palliative medicine, 33 2, 123-134Hughes, Jaime M; Freiermuth, Caroline E; Shepherd-Banigan, Megan; Ragsdale, Luna; Eucker, Stephanie A; Goldstein, Karen; Hastings, S Nicole; Rodriguez, Rachel L; Fulton, Jessica; Ramos, Katherine; Tabriz, Amir Alishahi; Gordon, Adelaide M; Gierisch, Jennifer M; Kosinski, Andrzej; Williams, John W 2019. Emergency Department Interventions for Older Adults: A Systematic Review. Journal of the American Geriatrics Society, 67 7, 1516-1525Cline, David M; Silva, Susan; Freiermuth, Caroline E; Thornton, Victoria; Tanabe, Paula 2018. Emergency Department (ED), ED Observation, Day Hospital, and Hospital Admissions for Adults with Sickle Cell Disease. The western journal of emergency medicine, 19 2, 311-318Gunn, Alexander H; Smothers, Zachary P W; Schramm-Sapyta, Nicole; Freiermuth, Caroline E; MacEachern, Mark; Muzyk, Andrew J 2018. The Emergency Department as an Opportunity for Naloxone Distribution. The western journal of emergency medicine, 19 6, 1036-1042Kopec, Kathryn T; Freiermuth, Caroline; Maynard, Susan; Beuhler, Michael 2018. Dinitrophenol (DNP) Fatality Associated with a Falsely Elevated Salicylate Level: a Case Report with Verification of Laboratory Cross Reactivity. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 14 4, 323-326Williams, Hants; Silva, R N Susan; Cline, David; Freiermuth, Caroline; Tanabe, Paula 2018. Social and Behavioral Factors in Sickle Cell Disease: Employment Predicts Decreased Health Care Utilization. Journal of health care for the poor and underserved, 29 2, 814-829Tanabe, Paula; Freiermuth, Caroline E; Cline, David M; Silva, Susan 2017. A Prospective Emergency Department Quality Improvement Project to Improve the Treatment of Vaso-Occlusive Crisis in Sickle Cell Disease: Lessons Learned. Joint Commission journal on quality and patient safety, 43 3, 116-126Freiermuth, Caroline E; Silva, Susan; Cline, David M; Tanabe, Paula 2016. Shift in Emergency Department Provider Attitudes Toward Patients With Sickle Cell Disease. Advanced emergency nursing journal, 38 3, 199-212Dedert, Eric A; McDuffie, Jennifer R; Stein, Roy; McNiel, J Murray; Kosinski, Andrzej S; Freiermuth, Caroline E; Hemminger, Adam; Williams, John W 2015. Electronic Interventions for Alcohol Misuse and Alcohol Use Disorders: A Systematic Review. Annals of internal medicine, 163 3, 205-14Freiermuth, Caroline E; Chandra, Abhinav; Peacock, W Frank 2015. Characteristics of patients that do not initially respond to intravenous antihypertensives in the emergency department: subanalysis of the CLUE trial. The western journal of emergency medicine, 16 2, 276-83Freiermuth, Caroline E; Haywood, Carlton; Silva, Susan; Cline, David M; Kayle, Mariam; Sullivan, Dori; Thornton, Victoria; Tanabe, Paula 2014. Attitudes toward patients with sickle cell disease in a multicenter sample of emergency department providers. Advanced emergency nursing journal, 36 4, 335-47Thornton, Victoria L; Holl, Jane L; Cline, David M; Freiermuth, Caroline E; Sullivan, Dori T; Tanabe, Paula 2014. Application of a proactive risk analysis to emergency department sickle cell care. The western journal of emergency medicine, 15 4, 446-58Blomkalns, Andra L; O'Connell, Elise M; Eady, Caroline E; Lindsell, Christopher J; Gibler, W Brian 2006. Evaluation of dyslipidemia in the emergency department: impact of cholesterol testing on subsequent therapy. American heart journal, 152 6, 1182-6Freiermuth C.E.;Silva S.;Cline D.M.;Tanabe P. 09-01-2016. Shift in Emergency Department Provider Attitudes Toward Patients with Sickle Cell Disease Advanced Emergency Nursing Journal, 38 3, 199-212Williams H.;Silva S.;Cline D.;Freiermuth C.;Tanabe P. 05-01-2018. Social and behavioral factors in sickle cell disease: Employment predicts decreased health care util Journal of Health Care for the Poor and Underserved, 29 2, 814-829Tanabe P.;Freiermuth C.E.;Cline D.M.;Silva S. 03-01-2017. A prospective emergency department quality improvement project to improve the treatment of vaso-occl Joint Commission Journal on Quality and Patient Safety, 43 3, 116-126Fulton J.J.;LeBlanc T.W.;Cutson T.M.;Porter Starr K.N.;Kamal A.;Ramos K.;Freiermuth C.E.;McDuffie J.R.;Kosinski A.;Adam S.;Nagi A.;Williams J.W. 02-01-2019. Integrated outpatient palliative care for patients with advanced cancer: A systematic review and met Palliative Medicine, 33 2, 123-134Freiermuth C.E.;Lavonas E.J.;Anderson V.E.;Kleinschmidt K.C.;Sharma K.;Rapp-Olsson M.;Gerardo C.;Bush S.;Mullins M.;Greene S.;Toschlog E.;Quackenbush E.;Rutherford Rose S.;Schwartz R.;Charlton N.;Lewis B.;Brandehoff N. 01-01-2019. Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation Western Journal of Emergency Medicine, 20 3, 497-505Hughes J.M.;Freiermuth C.E.;Shepherd-Banigan M.;Ragsdale L.;Eucker S.A.;Goldstein K.;Hastings S.N.;Rodriguez R.L.;Fulton J.;Ramos K.;Tabriz A.A.;Gordon A.M.;Gierisch J.M.;Kosinski A.;Williams J.W. 01-01-2019. Emergency Department Interventions for Older Adults: A Systematic Review Journal of the American Geriatrics Society, , Thornton V.;Holl J.;Cline D.;Freiermuth C.;Sullivan D.;Tanabe P. 01-01-2014. Application of a proactive risk analysis to emergency department sickle cell care Western Journal of Emergency Medicine, 15 4, 446-458Punches, Brittany E; Ali, Abeer Alhaj; Brown, Jennifer L; Freiermuth, Caroline E; Clark, Angela K; Lyons, Michael S . Opioid-Related Risk Screening Measures for the Emergency Care Setting. Advanced emergency nursing journal, 43 4, 331-343
Peer Reviewed Publications Brown, Jennifer L; Larochelle, Marc R; Fanucchi, Laura C; Calvert, Deirdre C; Campbell, Aimee N C; Chandler, Redonna K; Feaster, Daniel J; Glasgow, LaShawn M; Gibson, Erin B; Holloway, JaNae; Lofwall, Michelle R; Mack, Aimee; Mack, Nicole; Nunes, Edward V; Talbert, Jeffery C; Tan, Sylvia; Vandergrift, Nathan; Villani, Jennifer; Asman, Kat; Babakhanlou-Chase, Hermik; Bagley, Sarah M; Battaglia, Tracy A; Blevins, Derek; Bridden, Carly; Cheng, Debbie M; Christopher, Mia; Cogan, Lindsay W; Cunningham, Chinazo O; Eggleston, Barry; Fareed, Naleef; Fernandez, Soledad; Freedman, Darcy A; Freiermuth, Caroline E; Freisthler, Bridget; Gilbert, Louisa; Hammerslag, Lindsey; Harris, Daniel; Hunt, Timothy; Hussain, Shazia; Huynh, Phuong; Jackson, Rebecca D; Kauffman, Emily B; Knott, Charles; Knudsen, Hannah K; Lefebvre, R Craig; Levin, Frances R; Massatti, Rick; McAlearney, Ann Scheck; Morgan, Jake R; Lopez, Rosie Munoz; Lounsbury, David W; Newman, Lisa; Nickels, Katrina; Oga, Emmanuel A; Oller, Devin A; Parran, Theodore V; Quinn, Maria; Ramsey, Kelly S; Rapkin, Bruce D; Salsberry, Pamela; Stein, Michael; Taylor, Jessica L; Teater, Julie; Walters, Scott T; Zarkin, Gary A; El-Bassel, Nabila; Winhusen, T John; Samet, Jeffrey H; Walsh, Sharon L 2025. Effects of the Communities That HEAL intervention on initiation, retention, and linkage to medications for opioid use disorder (MOUD): A cluster randomized wait-list controlled trial. Drug and alcohol dependence, 274 , 112785Ibemere, Stephanie O; Barnhart, Huiman; Myers, John; Miller, Joseph; Osunkwo, Ifeyinwa; Bosworth, Hayden B; Freiermuth, Caroline E; Hughes, Robert; Kavanagh, Patricia L; Paice, Judith A; Paxton, James; Pierce, Ava; Runyon, Michael S; Strouse, John J; Veeramreddy, Padmaja; Wilkerson, R Gentry; Tanabe, Paula 2025. Impact of Individualized Versus Weight-Based Pain Protocols on Patient Satisfaction for Patients With Sickle Cell Disease Experiencing a Vaso-Occlusive Episode. Journal of emergency nursing, 51 4, 626-635McMonagle, Brianna N; Braun, Robert; Luke, Jude; Goel, Anita; Freiermuth, Caroline 2025. Patient Acceptance of Rapid HIV Testing During Targeted Screening in the Emergency Department. The western journal of emergency medicine, 26 4, 1124-1126Petrovitch, Dan; Himes, Katie P; Bischof, Jason J; Braun, Robert S; Brown, Jennifer L; Eleda, Isaiah C; Freiermuth, Caroline E; Gu, Shaopeng; Hall, O Trent; Johnson, Julie A; Kisor, David F; Lambert, Joshua W; Lyons, Michael S; Maloney, Morgan V; Punches, Brittany E; Quarles, Emma; Littlefield, Andrew K; Sprague, Jon E 2025. Scoping review of associations between cytochrome P450 3A4/5 single nucleotide polymorphisms and risk factors for fentanyl overdose. Pharmacogenomics, , 1-35Petrovitch, Dan; Himes, Katie P; Quarles, Emma; Freiermuth, Caroline E; Braun, Robert S; Lambert, Joshua W; Brown, Jennifer L; Lyons, Michael S; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2025. Negative urgency accounts for associations between internalizing symptoms and lifetime nonfatal opioid overdose among patients from three urban Ohio emergency departments. Experimental and clinical psychopharmacology, 33 3, 300-309Sabedra, Alexa; Freiermuth, Caroline; Santen, Sally; Leenellett, Elizabeth 2025. Faculty development committee: Evolution through engagement and empowerment. AEM education and training, 9 Suppl 1, S66-S72, ; Samet, Jeffrey H; El-Bassel, Nabila; Winhusen, T John; Jackson, Rebecca D; Oga, Emmanuel A; Chandler, Redonna K; Villani, Jennifer; Freisthler, Bridget; Adams, Joella; Aldridge, Arnie; Angerame, Angelo; Babineau, Denise C; Bagley, Sarah M; Baker, Trevor J; Balvanz, Peter; Barbosa, Carolina; Barocas, Joshua; Battaglia, Tracy A; Beard, Dacia D; Beers, Donna; Blevins, Derek; Bove, Nicholas; Bridden, Carly; Brown, Jennifer L; Bush, Heather M; Bush, Joshua L; Caldwell, Ryan; Calver, Katherine; Calvert, Deirdre; Campbell, Aimee N C; Carpenter, Jane; Caspar, Rachel; Chassler, Deborah; Chaya, Joan; Cheng, Debbie M; Cunningham, Chinazo O; Dasgupta, Anindita; David, James L; Davis, Alissa; Dean, Tammy; Drainoni, Mari-Lynn; Eggleston, Barry; Fanucchi, Laura C; Feaster, Daniel J; Fernandez, Soledad; Figueroa, Wilson; Freedman, Darcy A; Freeman, Patricia R; Freiermuth, Caroline E; Friedlander, Eric; Gelberg, Kitty H; Gibson, Erin B; Gilbert, Louisa; Glasgow, LaShawn; Goddard-Eckrich, Dawn A; Gomori, Stephen; Gruss, Dawn E; Gulley, Jennifer; Gutnick, Damara; Hall, Megan E; Harger Dykes, Nicole; Hargrove, Sarah L; Harlow, Kristin; Harris, Aumani; Harris, Daniel; Helme, Donald W; Holloway, JaNae; Hotchkiss, Juanita; Huang, Terry; Huerta, Timothy R; Hunt, Timothy; Hyder, Ayaz; Ingram, Van L; Ingram, Tim; Kauffman, Emily; Kimball, Jennifer L; Kinnard, Elizabeth N; Knott, Charles; Knudsen, Hannah K; Konstan, Michael W; Kosakowski, Sarah; Larochelle, Marc R; Leaver, Hannah M; LeBaron, Patricia A; Lefebvre, R Craig; Levin, Frances R; Lewis, Nikki; Lewis, Nicky; Lofwall, Michelle R; Lounsbury, David W; Luster, Jamie E; Lyons, Michael S; Mack, Aimee; Marks, Katherine R; Marquesano, Stephanie; Mauk, Rachel; McAlearney, Ann Scheck; McConnell, Kristin; McGladrey, Margaret L; McMullan, Jason; Miles, Jennifer; Munoz Lopez, Rosie; Nelson, Alisha; Neufeld, Jessica L; Newman, Lisa; Nguyen, Trang Q; Nunes, Edward V; Oller, Devin A; Oser, Carrie B; Oyler, Douglas R; Pagnano, Sharon; Parran, Theodore V; Powell, Joshua; Powers, Kim; Ralston, William; Ramsey, Kelly; Rapkin, Bruce D; Reynolds, Jennifer G; Roberts, Monica F; Robertson, Will; Rock, Peter; Rodgers, Emma; Rodriguez, Sandra; Rudorf, Maria; Ryan, Shawn; Salsberry, Pamela; Salvage, Monika; Sabounchi, Nasim; Saucier, Merielle; Savitzky, Caroline; Schackman, Bruce; Schady, Elizabeth; Seiber, Eric E; Shadwick, Aimee; Shoben, Abigail; Slater, Michael D; Slavova, Svetla; Speer, Drew; Sprunger, Joel; Starbird, Laura E; Staton, Michele; Stein, Michael D; Stevens-Watkins, Danelle J; Stopka, Thomas J; Sullivan, Ann; Surratt, Hilary L; Sword Cruz, Rachel; Talbert, Jeffery C; Taylor, Jessica L; Thompson, Katherine L; Vandergrift, Nathan; Vickers-Smith, Rachel A; Vietze, Deanna J; Walker, Daniel M; Walley, Alexander Y; Walters, Scott T; Weiss, Roger; Westgate, Philip M; Wu, Elwin; Young, April M; Zarkin, Gary A; Walsh, Sharon L 2024. Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths. The New England journal of medicine, 391 11, 989-1001Freiermuth, Caroline E; Foster, Jenny A; Manandhar, Pratik; Arulraja, Evangeline; Erkanli, Alaattin; Pollack, Charles V; Eucker, Stephanie A 2024. Opioid Treatment Is Associated with Recurrent Healthcare Visits, Increased Side Effects, and Pain. The western journal of emergency medicine, 25 6, 875-882Himes, Katie P; Dan Petrovitch, M A; Freiermuth, Caroline E; Bachmann, Daniel J; Bischof, Jason J; Braun, Robert S; Brown, Jennifer L; Frey, Jennifer A; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2024. Are opioid use disorder assessments in the emergency department biased? An examination across sex, race, and employment status using item response theory. General hospital psychiatry, 91 , 186-189Lambert, Joshua; Petrovitch, Dan; Himes, Katie P; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Bischof, Jason J; Lyons, Michael S; Punches, Brittany E; Littlefield, Andrew K; Kisor, David F; Sprague, Jon E 2024. Association of genetic variants in CYP3A5, DRD2 and NK1R with opioid overdose. Chemico-biological interactions, 403 , 111242Littlefield, Andrew K; Himes, Katie P; Petrovitch, Dan; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Bischof, Jason J; Punches, Brittany E; Sprague, Jon E 2024. The relations between impulsivity, opioid use, and nonmedical prescription opioid use motives: An examination within three large urban emergency departments. Experimental and clinical psychopharmacology, 32 6, 652-663Petrovitch, Dan; Himes, Katie P; Jump, Alayna; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Lyons, Michael S; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2024. State program enables the identification of factors associated with naloxone awareness, self-efficacy, and use for overdose reversal: A cross-sectional, observational study in an urban emergency department population. Journal of substance use and addiction treatment, 167 , 209506Punches, Brittany E; Freiermuth, Caroline E; Sprague, Jon E; Brown, Jennifer L; Hutzel-Dunham, Elizabeth; Lambert, Joshua; Braun, Robert; Littlefield, Andrew; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Pantalon, Michael V; Ancona, Rachel M; Kisor, David F; Lyons, Michael S 2024. Screening for problematic opioid use in the emergency department: Comparison of two screening measures. Journal of the American College of Emergency Physicians open, 5 1, e13106Sprague, Jon E; Freiermuth, Caroline E; Lambert, Joshua; Braun, Robert; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Beaumont, Lauren; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Ancona, Rachel; Kisor, David F 2024. Opioid use disorder risk alleles in self-reported assigned African American/Afro-Caribbean and European biogeographical genetic ancestry groups and in males and females. The pharmacogenomics journal, 24 4, 23D'Onofrio, Gail; Edelman, E Jennifer; Hawk, Kathryn F; Chawarski, Marek C; Pantalon, Michael V; Owens, Patricia H; Martel, Shara H; Rothman, Richard; Saheed, Mustapha; Schwartz, Robert P; Cowan, Ethan; Richardson, Lynne; Salsitz, Edwin; Lyons, Michael S; Freiermuth, Caroline; Wilder, Christine; Whiteside, Lauren; Tsui, Judith I; Klein, Jared W; Coupet, Edouard; O'Connor, Patrick G; Matthews, Abigail G; Murphy, Sean M; Huntley, Kristen; Fiellin, David A 2023. Implementation Facilitation to Promote Emergency Department-Initiated Buprenorphine for Opioid Use Disorder. JAMA network open, 6 4, e235439Freiermuth, Caroline E; Ancona, Rachel M; Brown, Jennifer L; Punches, Brittany E; Ryan, Shawn A; Ingram, Tim; Lyons, Michael S 2023. Evaluation of a large-scale health department naloxone distribution program: Per capita naloxone distribution and overdose morality. PloS one, 18 8, e0289959Freiermuth, Caroline E; Kisor, David F; Lambert, Joshua; Braun, Robert; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Ancona, Rachel; Sprague, Jon E 2023. Genetic Variants Associated With Opioid Use Disorder. Clinical pharmacology and therapeutics, 113 5, 1089-1095Tanabe, Paula; Ibemere, Stephanie; Pierce, Ava E; Freiermuth, Caroline E; Bosworth, Hayden B; Yang, Hongqui; Osunkwo, Ifeyinwa; Paxton, James H; Strouse, John J; Miller, Joseph; Paice, Judith A; Veeramreddy, Padmaja; Kavanagh, Patricia L; Wilkerson, R Gentry; Hughes, Robert; Barnhart, Huiman X 2023. A comparison of the effect of patient-specific versus weight-based protocols to treat vaso-occlusive episodes in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 30 12, 1210-1222Bellolio, Fernanda; Broder, Joshua S; Oliveira J E Silva, Lucas; Freiermuth, Caroline E; Hooker, Edmond; Jang, Timothy B; Griffey, Richard T; Meltzer, Andrew C; Mills, Angela M; Pepper, Joan; Prakken, Steven; Repplinger, Michael D; Upadhye, Suneel; Carpenter, Christopher R 2022. Reply to "Letter to the Editor, re: GRACE-2: Low-Risk, Recurrent Abdominal Pain in the Emergency Department". Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 29 9, 1148-1150Broder, Joshua S; Oliveira J E Silva, Lucas; Bellolio, Fernanda; Freiermuth, Caroline E; Griffey, Richard T; Hooker, Edmond; Jang, Timothy B; Meltzer, Andrew C; Mills, Angela M; Pepper, Joan D; Prakken, Steven D; Repplinger, Michael D; Upadhye, Suneel; Carpenter, Christopher R 2022. Guidelines for Reasonable and Appropriate Care in the Emergency Department 2 (GRACE-2): Low-risk, recurrent abdominal pain in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 29 5, 526-560Faryar, Kiran A; Braun, Robert; Ancona, Rachel M; Freiermuth, Caroline; Lyons, Michael S 2022. Acceptance of HIV pre-exposure prophylaxis (PrEP) referral among a sample of PrEP-eligible emergency department patients. The American journal of emergency medicine, 60 , 152-155Ojeda, Myriam Shaw; Chen, Aleda M H; Miracle, Tessa; Delaney, Elizabeth; Freiermuth, Caroline E; Sprague, Jon E 2022. HealthCare educational differences in pain management, adverse childhood experiences and their relationship to substance use disorder education. Substance abuse treatment, prevention, and policy, 17 1, 10Punches, Brittany E; Brown, Jennifer L; Soliman, Summer; Johnson, Kimberly D; Freiermuth, Caroline E; Walker, Quinn; Omololu, Shammah O; Lyons, Michael S 2022. Patient Pain Experiences and the Emergency Department Encounter: A Qualitative Analysis. Pain management nursing : official journal of the American Society of Pain Management Nurses, 23 4, 391-396Punches, Brittany E; Stolz, Uwe; Freiermuth, Caroline E; Ancona, Rachel M; McLean, Samuel A; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Zeng, Donglin; Neylan, Thomas C; Clifford, Gari D; Jovanovic, Tanja; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Kurz, Michael C; Gentile, Nina T; McGrath, Meghan E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Chang, Anna M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Pietrzak, Robert H; Joormann, Jutta; Barch, Deanna M; Pizzagalli, Diego A; Smoller, Jordan W; Luna, Beatriz; Harte, Steven E; Elliott, James M; Kessler, Ronald C; Ressler, Kerry J; Koenen, Karestan C; Lyons, Michael S 2022. Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study. PloS one, 17 9, e0273378Westafer, Lauren M; Freiermuth, Caroline E; Lall, Michelle D; Muder, Sarah J; Ragone, Eleanor L; Jarman, Angela F 2022. Experiences of Transgender and Gender Expansive Physicians. JAMA network open, 5 6, e2219791Whiteside, Lauren K; D'Onofrio, Gail; Fiellin, David A; Edelman, E Jennifer; Richardson, Lynne; O'Connor, Patrick; Rothman, Richard E; Cowan, Ethan; Lyons, Michael S; Fockele, Callan E; Saheed, Mustapha; Freiermuth, Caroline; Punches, Brittany E; Guo, Clara; Martel, Shara; Owens, Patricia H; Coupet, Edouard; Hawk, Kathryn F 2022. Models for Implementing Emergency Department-Initiated Buprenorphine With Referral for Ongoing Medication Treatment at Emergency Department Discharge in Diverse Academic Centers. Annals of emergency medicine, 80 5, 410-419Eucker, Stephanie A; Manandhar, Pratik; Arulraja, Kami; Agnihotri, Deepti; Pollack, Charles V; Freiermuth, Caroline 2021. Higher daily pain severity after emergency department visits is associated with lower return-to-work rates. The American journal of emergency medicine, 45 , 48-53Ibemere, Stephanie O; Dubbs, Sarah B; Barnhart, Huiman X; Brown, Jacqueline L; Freiermuth, Caroline E; Kavanagh, Patricia; Paice, Judith A; Strouse, John J; Wilkerson, R Gentry; Tanabe, Paula 2021. Trial design of comparing patient-specific versus weight-based protocols to treat vaso-occlusive episodes in sickle cell disease (COMPARE-VOE). Contemporary clinical trials, 101 , 106252Lane, Bennett H; Lyons, Michael S; Stolz, Uwe; Ancona, Rachel M; Ryan, Richard J; Freiermuth, Caroline E 2021. Naloxone provision to emergency department patients recognized as high-risk for opioid use disorder. The American journal of emergency medicine, 40 , 173-176McCorkle, Maggie L; Kisor, David F; Freiermuth, Caroline E; Sprague, Jon E 2021. Systematic review of Pharmacogenomics Knowledgebase evidence for pharmacogenomic links to the dopamine reward pathway for heroin dependence. Pharmacogenomics, 22 13, 849-857Punches, Brittany E; Ancona, Rachel M; Freiermuth, Caroline E; Brown, Jennifer L; Lyons, Michael S 2021. Incidence of opioid use disorder in the year after discharge from an emergency department encounter. Journal of the American College of Emergency Physicians open, 2 3, e12476Punches, Brittany E; Berger, Kimberly M; Freiermuth, Caroline E; Soliman, Summer A; Walker, Quinn T; Lyons, Michael S 2021. Emergency Nurse Perceptions of Pain and Opioids in the Emergency Department. Pain management nursing : official journal of the American Society of Pain Management Nurses, 22 5, 586-591Punches, Brittany E; Soliman, Summer; Freiermuth, Caroline E; Lane, Bennett H; Lyons, Michael S 2020. Emergency Nurse Perceptions of Naloxone Distribution in the Emergency Department. Journal of emergency nursing, 46 5, 675-681.e1Freiermuth, Caroline E; Lavonas, Eric J; Anderson, Victoria E; Kleinschmidt, Kurt C; Sharma, Kapil; Rapp-Olsson, Malin; Gerardo, Charles 2019. Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation. The western journal of emergency medicine, 20 3, 497-505Fulton, Jessica J; LeBlanc, Thomas W; Cutson, Toni M; Porter Starr, Kathryn N; Kamal, Arif; Ramos, Katherine; Freiermuth, Caroline E; McDuffie, Jennifer R; Kosinski, Andrzej; Adam, Soheir; Nagi, Avishek; Williams, John W 2019. Integrated outpatient palliative care for patients with advanced cancer: A systematic review and meta-analysis. Palliative medicine, 33 2, 123-134Hughes, Jaime M; Freiermuth, Caroline E; Shepherd-Banigan, Megan; Ragsdale, Luna; Eucker, Stephanie A; Goldstein, Karen; Hastings, S Nicole; Rodriguez, Rachel L; Fulton, Jessica; Ramos, Katherine; Tabriz, Amir Alishahi; Gordon, Adelaide M; Gierisch, Jennifer M; Kosinski, Andrzej; Williams, John W 2019. Emergency Department Interventions for Older Adults: A Systematic Review. Journal of the American Geriatrics Society, 67 7, 1516-1525Cline, David M; Silva, Susan; Freiermuth, Caroline E; Thornton, Victoria; Tanabe, Paula 2018. Emergency Department (ED), ED Observation, Day Hospital, and Hospital Admissions for Adults with Sickle Cell Disease. The western journal of emergency medicine, 19 2, 311-318Gunn, Alexander H; Smothers, Zachary P W; Schramm-Sapyta, Nicole; Freiermuth, Caroline E; MacEachern, Mark; Muzyk, Andrew J 2018. The Emergency Department as an Opportunity for Naloxone Distribution. The western journal of emergency medicine, 19 6, 1036-1042Kopec, Kathryn T; Freiermuth, Caroline; Maynard, Susan; Beuhler, Michael 2018. Dinitrophenol (DNP) Fatality Associated with a Falsely Elevated Salicylate Level: a Case Report with Verification of Laboratory Cross Reactivity. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 14 4, 323-326Williams, Hants; Silva, R N Susan; Cline, David; Freiermuth, Caroline; Tanabe, Paula 2018. Social and Behavioral Factors in Sickle Cell Disease: Employment Predicts Decreased Health Care Utilization. Journal of health care for the poor and underserved, 29 2, 814-829Tanabe, Paula; Freiermuth, Caroline E; Cline, David M; Silva, Susan 2017. A Prospective Emergency Department Quality Improvement Project to Improve the Treatment of Vaso-Occlusive Crisis in Sickle Cell Disease: Lessons Learned. Joint Commission journal on quality and patient safety, 43 3, 116-126Freiermuth, Caroline E; Silva, Susan; Cline, David M; Tanabe, Paula 2016. Shift in Emergency Department Provider Attitudes Toward Patients With Sickle Cell Disease. Advanced emergency nursing journal, 38 3, 199-212Dedert, Eric A; McDuffie, Jennifer R; Stein, Roy; McNiel, J Murray; Kosinski, Andrzej S; Freiermuth, Caroline E; Hemminger, Adam; Williams, John W 2015. Electronic Interventions for Alcohol Misuse and Alcohol Use Disorders: A Systematic Review. Annals of internal medicine, 163 3, 205-14Freiermuth, Caroline E; Chandra, Abhinav; Peacock, W Frank 2015. Characteristics of patients that do not initially respond to intravenous antihypertensives in the emergency department: subanalysis of the CLUE trial. The western journal of emergency medicine, 16 2, 276-83Freiermuth, Caroline E; Haywood, Carlton; Silva, Susan; Cline, David M; Kayle, Mariam; Sullivan, Dori; Thornton, Victoria; Tanabe, Paula 2014. Attitudes toward patients with sickle cell disease in a multicenter sample of emergency department providers. Advanced emergency nursing journal, 36 4, 335-47Thornton, Victoria L; Holl, Jane L; Cline, David M; Freiermuth, Caroline E; Sullivan, Dori T; Tanabe, Paula 2014. Application of a proactive risk analysis to emergency department sickle cell care. The western journal of emergency medicine, 15 4, 446-58Blomkalns, Andra L; O'Connell, Elise M; Eady, Caroline E; Lindsell, Christopher J; Gibler, W Brian 2006. Evaluation of dyslipidemia in the emergency department: impact of cholesterol testing on subsequent therapy. American heart journal, 152 6, 1182-6Freiermuth C.E.;Silva S.;Cline D.M.;Tanabe P. 09-01-2016. Shift in Emergency Department Provider Attitudes Toward Patients with Sickle Cell Disease Advanced Emergency Nursing Journal, 38 3, 199-212Williams H.;Silva S.;Cline D.;Freiermuth C.;Tanabe P. 05-01-2018. Social and behavioral factors in sickle cell disease: Employment predicts decreased health care util Journal of Health Care for the Poor and Underserved, 29 2, 814-829Tanabe P.;Freiermuth C.E.;Cline D.M.;Silva S. 03-01-2017. A prospective emergency department quality improvement project to improve the treatment of vaso-occl Joint Commission Journal on Quality and Patient Safety, 43 3, 116-126Fulton J.J.;LeBlanc T.W.;Cutson T.M.;Porter Starr K.N.;Kamal A.;Ramos K.;Freiermuth C.E.;McDuffie J.R.;Kosinski A.;Adam S.;Nagi A.;Williams J.W. 02-01-2019. Integrated outpatient palliative care for patients with advanced cancer: A systematic review and met Palliative Medicine, 33 2, 123-134Freiermuth C.E.;Lavonas E.J.;Anderson V.E.;Kleinschmidt K.C.;Sharma K.;Rapp-Olsson M.;Gerardo C.;Bush S.;Mullins M.;Greene S.;Toschlog E.;Quackenbush E.;Rutherford Rose S.;Schwartz R.;Charlton N.;Lewis B.;Brandehoff N. 01-01-2019. Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation Western Journal of Emergency Medicine, 20 3, 497-505Hughes J.M.;Freiermuth C.E.;Shepherd-Banigan M.;Ragsdale L.;Eucker S.A.;Goldstein K.;Hastings S.N.;Rodriguez R.L.;Fulton J.;Ramos K.;Tabriz A.A.;Gordon A.M.;Gierisch J.M.;Kosinski A.;Williams J.W. 01-01-2019. Emergency Department Interventions for Older Adults: A Systematic Review Journal of the American Geriatrics Society, , Thornton V.;Holl J.;Cline D.;Freiermuth C.;Sullivan D.;Tanabe P. 01-01-2014. Application of a proactive risk analysis to emergency department sickle cell care Western Journal of Emergency Medicine, 15 4, 446-458Punches, Brittany E; Ali, Abeer Alhaj; Brown, Jennifer L; Freiermuth, Caroline E; Clark, Angela K; Lyons, Michael S . Opioid-Related Risk Screening Measures for the Emergency Care Setting. Advanced emergency nursing journal, 43 4, 331-343
Brown, Jennifer L; Larochelle, Marc R; Fanucchi, Laura C; Calvert, Deirdre C; Campbell, Aimee N C; Chandler, Redonna K; Feaster, Daniel J; Glasgow, LaShawn M; Gibson, Erin B; Holloway, JaNae; Lofwall, Michelle R; Mack, Aimee; Mack, Nicole; Nunes, Edward V; Talbert, Jeffery C; Tan, Sylvia; Vandergrift, Nathan; Villani, Jennifer; Asman, Kat; Babakhanlou-Chase, Hermik; Bagley, Sarah M; Battaglia, Tracy A; Blevins, Derek; Bridden, Carly; Cheng, Debbie M; Christopher, Mia; Cogan, Lindsay W; Cunningham, Chinazo O; Eggleston, Barry; Fareed, Naleef; Fernandez, Soledad; Freedman, Darcy A; Freiermuth, Caroline E; Freisthler, Bridget; Gilbert, Louisa; Hammerslag, Lindsey; Harris, Daniel; Hunt, Timothy; Hussain, Shazia; Huynh, Phuong; Jackson, Rebecca D; Kauffman, Emily B; Knott, Charles; Knudsen, Hannah K; Lefebvre, R Craig; Levin, Frances R; Massatti, Rick; McAlearney, Ann Scheck; Morgan, Jake R; Lopez, Rosie Munoz; Lounsbury, David W; Newman, Lisa; Nickels, Katrina; Oga, Emmanuel A; Oller, Devin A; Parran, Theodore V; Quinn, Maria; Ramsey, Kelly S; Rapkin, Bruce D; Salsberry, Pamela; Stein, Michael; Taylor, Jessica L; Teater, Julie; Walters, Scott T; Zarkin, Gary A; El-Bassel, Nabila; Winhusen, T John; Samet, Jeffrey H; Walsh, Sharon L 2025. Effects of the Communities That HEAL intervention on initiation, retention, and linkage to medications for opioid use disorder (MOUD): A cluster randomized wait-list controlled trial. Drug and alcohol dependence, 274 , 112785Ibemere, Stephanie O; Barnhart, Huiman; Myers, John; Miller, Joseph; Osunkwo, Ifeyinwa; Bosworth, Hayden B; Freiermuth, Caroline E; Hughes, Robert; Kavanagh, Patricia L; Paice, Judith A; Paxton, James; Pierce, Ava; Runyon, Michael S; Strouse, John J; Veeramreddy, Padmaja; Wilkerson, R Gentry; Tanabe, Paula 2025. Impact of Individualized Versus Weight-Based Pain Protocols on Patient Satisfaction for Patients With Sickle Cell Disease Experiencing a Vaso-Occlusive Episode. Journal of emergency nursing, 51 4, 626-635McMonagle, Brianna N; Braun, Robert; Luke, Jude; Goel, Anita; Freiermuth, Caroline 2025. Patient Acceptance of Rapid HIV Testing During Targeted Screening in the Emergency Department. The western journal of emergency medicine, 26 4, 1124-1126Petrovitch, Dan; Himes, Katie P; Bischof, Jason J; Braun, Robert S; Brown, Jennifer L; Eleda, Isaiah C; Freiermuth, Caroline E; Gu, Shaopeng; Hall, O Trent; Johnson, Julie A; Kisor, David F; Lambert, Joshua W; Lyons, Michael S; Maloney, Morgan V; Punches, Brittany E; Quarles, Emma; Littlefield, Andrew K; Sprague, Jon E 2025. Scoping review of associations between cytochrome P450 3A4/5 single nucleotide polymorphisms and risk factors for fentanyl overdose. Pharmacogenomics, , 1-35Petrovitch, Dan; Himes, Katie P; Quarles, Emma; Freiermuth, Caroline E; Braun, Robert S; Lambert, Joshua W; Brown, Jennifer L; Lyons, Michael S; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2025. Negative urgency accounts for associations between internalizing symptoms and lifetime nonfatal opioid overdose among patients from three urban Ohio emergency departments. Experimental and clinical psychopharmacology, 33 3, 300-309Sabedra, Alexa; Freiermuth, Caroline; Santen, Sally; Leenellett, Elizabeth 2025. Faculty development committee: Evolution through engagement and empowerment. AEM education and training, 9 Suppl 1, S66-S72, ; Samet, Jeffrey H; El-Bassel, Nabila; Winhusen, T John; Jackson, Rebecca D; Oga, Emmanuel A; Chandler, Redonna K; Villani, Jennifer; Freisthler, Bridget; Adams, Joella; Aldridge, Arnie; Angerame, Angelo; Babineau, Denise C; Bagley, Sarah M; Baker, Trevor J; Balvanz, Peter; Barbosa, Carolina; Barocas, Joshua; Battaglia, Tracy A; Beard, Dacia D; Beers, Donna; Blevins, Derek; Bove, Nicholas; Bridden, Carly; Brown, Jennifer L; Bush, Heather M; Bush, Joshua L; Caldwell, Ryan; Calver, Katherine; Calvert, Deirdre; Campbell, Aimee N C; Carpenter, Jane; Caspar, Rachel; Chassler, Deborah; Chaya, Joan; Cheng, Debbie M; Cunningham, Chinazo O; Dasgupta, Anindita; David, James L; Davis, Alissa; Dean, Tammy; Drainoni, Mari-Lynn; Eggleston, Barry; Fanucchi, Laura C; Feaster, Daniel J; Fernandez, Soledad; Figueroa, Wilson; Freedman, Darcy A; Freeman, Patricia R; Freiermuth, Caroline E; Friedlander, Eric; Gelberg, Kitty H; Gibson, Erin B; Gilbert, Louisa; Glasgow, LaShawn; Goddard-Eckrich, Dawn A; Gomori, Stephen; Gruss, Dawn E; Gulley, Jennifer; Gutnick, Damara; Hall, Megan E; Harger Dykes, Nicole; Hargrove, Sarah L; Harlow, Kristin; Harris, Aumani; Harris, Daniel; Helme, Donald W; Holloway, JaNae; Hotchkiss, Juanita; Huang, Terry; Huerta, Timothy R; Hunt, Timothy; Hyder, Ayaz; Ingram, Van L; Ingram, Tim; Kauffman, Emily; Kimball, Jennifer L; Kinnard, Elizabeth N; Knott, Charles; Knudsen, Hannah K; Konstan, Michael W; Kosakowski, Sarah; Larochelle, Marc R; Leaver, Hannah M; LeBaron, Patricia A; Lefebvre, R Craig; Levin, Frances R; Lewis, Nikki; Lewis, Nicky; Lofwall, Michelle R; Lounsbury, David W; Luster, Jamie E; Lyons, Michael S; Mack, Aimee; Marks, Katherine R; Marquesano, Stephanie; Mauk, Rachel; McAlearney, Ann Scheck; McConnell, Kristin; McGladrey, Margaret L; McMullan, Jason; Miles, Jennifer; Munoz Lopez, Rosie; Nelson, Alisha; Neufeld, Jessica L; Newman, Lisa; Nguyen, Trang Q; Nunes, Edward V; Oller, Devin A; Oser, Carrie B; Oyler, Douglas R; Pagnano, Sharon; Parran, Theodore V; Powell, Joshua; Powers, Kim; Ralston, William; Ramsey, Kelly; Rapkin, Bruce D; Reynolds, Jennifer G; Roberts, Monica F; Robertson, Will; Rock, Peter; Rodgers, Emma; Rodriguez, Sandra; Rudorf, Maria; Ryan, Shawn; Salsberry, Pamela; Salvage, Monika; Sabounchi, Nasim; Saucier, Merielle; Savitzky, Caroline; Schackman, Bruce; Schady, Elizabeth; Seiber, Eric E; Shadwick, Aimee; Shoben, Abigail; Slater, Michael D; Slavova, Svetla; Speer, Drew; Sprunger, Joel; Starbird, Laura E; Staton, Michele; Stein, Michael D; Stevens-Watkins, Danelle J; Stopka, Thomas J; Sullivan, Ann; Surratt, Hilary L; Sword Cruz, Rachel; Talbert, Jeffery C; Taylor, Jessica L; Thompson, Katherine L; Vandergrift, Nathan; Vickers-Smith, Rachel A; Vietze, Deanna J; Walker, Daniel M; Walley, Alexander Y; Walters, Scott T; Weiss, Roger; Westgate, Philip M; Wu, Elwin; Young, April M; Zarkin, Gary A; Walsh, Sharon L 2024. Community-Based Cluster-Randomized Trial to Reduce Opioid Overdose Deaths. The New England journal of medicine, 391 11, 989-1001Freiermuth, Caroline E; Foster, Jenny A; Manandhar, Pratik; Arulraja, Evangeline; Erkanli, Alaattin; Pollack, Charles V; Eucker, Stephanie A 2024. Opioid Treatment Is Associated with Recurrent Healthcare Visits, Increased Side Effects, and Pain. The western journal of emergency medicine, 25 6, 875-882Himes, Katie P; Dan Petrovitch, M A; Freiermuth, Caroline E; Bachmann, Daniel J; Bischof, Jason J; Braun, Robert S; Brown, Jennifer L; Frey, Jennifer A; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2024. Are opioid use disorder assessments in the emergency department biased? An examination across sex, race, and employment status using item response theory. General hospital psychiatry, 91 , 186-189Lambert, Joshua; Petrovitch, Dan; Himes, Katie P; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Bischof, Jason J; Lyons, Michael S; Punches, Brittany E; Littlefield, Andrew K; Kisor, David F; Sprague, Jon E 2024. Association of genetic variants in CYP3A5, DRD2 and NK1R with opioid overdose. Chemico-biological interactions, 403 , 111242Littlefield, Andrew K; Himes, Katie P; Petrovitch, Dan; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Bischof, Jason J; Punches, Brittany E; Sprague, Jon E 2024. The relations between impulsivity, opioid use, and nonmedical prescription opioid use motives: An examination within three large urban emergency departments. Experimental and clinical psychopharmacology, 32 6, 652-663Petrovitch, Dan; Himes, Katie P; Jump, Alayna; Freiermuth, Caroline E; Braun, Robert S; Brown, Jennifer L; Lyons, Michael S; Punches, Brittany E; Sprague, Jon E; Littlefield, Andrew K 2024. State program enables the identification of factors associated with naloxone awareness, self-efficacy, and use for overdose reversal: A cross-sectional, observational study in an urban emergency department population. Journal of substance use and addiction treatment, 167 , 209506Punches, Brittany E; Freiermuth, Caroline E; Sprague, Jon E; Brown, Jennifer L; Hutzel-Dunham, Elizabeth; Lambert, Joshua; Braun, Robert; Littlefield, Andrew; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Pantalon, Michael V; Ancona, Rachel M; Kisor, David F; Lyons, Michael S 2024. Screening for problematic opioid use in the emergency department: Comparison of two screening measures. Journal of the American College of Emergency Physicians open, 5 1, e13106Sprague, Jon E; Freiermuth, Caroline E; Lambert, Joshua; Braun, Robert; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Beaumont, Lauren; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Ancona, Rachel; Kisor, David F 2024. Opioid use disorder risk alleles in self-reported assigned African American/Afro-Caribbean and European biogeographical genetic ancestry groups and in males and females. The pharmacogenomics journal, 24 4, 23D'Onofrio, Gail; Edelman, E Jennifer; Hawk, Kathryn F; Chawarski, Marek C; Pantalon, Michael V; Owens, Patricia H; Martel, Shara H; Rothman, Richard; Saheed, Mustapha; Schwartz, Robert P; Cowan, Ethan; Richardson, Lynne; Salsitz, Edwin; Lyons, Michael S; Freiermuth, Caroline; Wilder, Christine; Whiteside, Lauren; Tsui, Judith I; Klein, Jared W; Coupet, Edouard; O'Connor, Patrick G; Matthews, Abigail G; Murphy, Sean M; Huntley, Kristen; Fiellin, David A 2023. Implementation Facilitation to Promote Emergency Department-Initiated Buprenorphine for Opioid Use Disorder. JAMA network open, 6 4, e235439Freiermuth, Caroline E; Ancona, Rachel M; Brown, Jennifer L; Punches, Brittany E; Ryan, Shawn A; Ingram, Tim; Lyons, Michael S 2023. Evaluation of a large-scale health department naloxone distribution program: Per capita naloxone distribution and overdose morality. PloS one, 18 8, e0289959Freiermuth, Caroline E; Kisor, David F; Lambert, Joshua; Braun, Robert; Frey, Jennifer A; Bachmann, Daniel J; Bischof, Jason J; Lyons, Michael S; Pantalon, Michael V; Punches, Brittany E; Ancona, Rachel; Sprague, Jon E 2023. Genetic Variants Associated With Opioid Use Disorder. Clinical pharmacology and therapeutics, 113 5, 1089-1095Tanabe, Paula; Ibemere, Stephanie; Pierce, Ava E; Freiermuth, Caroline E; Bosworth, Hayden B; Yang, Hongqui; Osunkwo, Ifeyinwa; Paxton, James H; Strouse, John J; Miller, Joseph; Paice, Judith A; Veeramreddy, Padmaja; Kavanagh, Patricia L; Wilkerson, R Gentry; Hughes, Robert; Barnhart, Huiman X 2023. A comparison of the effect of patient-specific versus weight-based protocols to treat vaso-occlusive episodes in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 30 12, 1210-1222Bellolio, Fernanda; Broder, Joshua S; Oliveira J E Silva, Lucas; Freiermuth, Caroline E; Hooker, Edmond; Jang, Timothy B; Griffey, Richard T; Meltzer, Andrew C; Mills, Angela M; Pepper, Joan; Prakken, Steven; Repplinger, Michael D; Upadhye, Suneel; Carpenter, Christopher R 2022. Reply to "Letter to the Editor, re: GRACE-2: Low-Risk, Recurrent Abdominal Pain in the Emergency Department". Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 29 9, 1148-1150Broder, Joshua S; Oliveira J E Silva, Lucas; Bellolio, Fernanda; Freiermuth, Caroline E; Griffey, Richard T; Hooker, Edmond; Jang, Timothy B; Meltzer, Andrew C; Mills, Angela M; Pepper, Joan D; Prakken, Steven D; Repplinger, Michael D; Upadhye, Suneel; Carpenter, Christopher R 2022. Guidelines for Reasonable and Appropriate Care in the Emergency Department 2 (GRACE-2): Low-risk, recurrent abdominal pain in the emergency department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 29 5, 526-560Faryar, Kiran A; Braun, Robert; Ancona, Rachel M; Freiermuth, Caroline; Lyons, Michael S 2022. Acceptance of HIV pre-exposure prophylaxis (PrEP) referral among a sample of PrEP-eligible emergency department patients. The American journal of emergency medicine, 60 , 152-155Ojeda, Myriam Shaw; Chen, Aleda M H; Miracle, Tessa; Delaney, Elizabeth; Freiermuth, Caroline E; Sprague, Jon E 2022. HealthCare educational differences in pain management, adverse childhood experiences and their relationship to substance use disorder education. Substance abuse treatment, prevention, and policy, 17 1, 10Punches, Brittany E; Brown, Jennifer L; Soliman, Summer; Johnson, Kimberly D; Freiermuth, Caroline E; Walker, Quinn; Omololu, Shammah O; Lyons, Michael S 2022. Patient Pain Experiences and the Emergency Department Encounter: A Qualitative Analysis. Pain management nursing : official journal of the American Society of Pain Management Nurses, 23 4, 391-396Punches, Brittany E; Stolz, Uwe; Freiermuth, Caroline E; Ancona, Rachel M; McLean, Samuel A; House, Stacey L; Beaudoin, Francesca L; An, Xinming; Stevens, Jennifer S; Zeng, Donglin; Neylan, Thomas C; Clifford, Gari D; Jovanovic, Tanja; Linnstaedt, Sarah D; Germine, Laura T; Bollen, Kenneth A; Rauch, Scott L; Haran, John P; Storrow, Alan B; Lewandowski, Christopher; Musey, Paul I; Hendry, Phyllis L; Sheikh, Sophia; Jones, Christopher W; Kurz, Michael C; Gentile, Nina T; McGrath, Meghan E; Hudak, Lauren A; Pascual, Jose L; Seamon, Mark J; Harris, Erica; Chang, Anna M; Pearson, Claire; Peak, David A; Merchant, Roland C; Domeier, Robert M; Rathlev, Niels K; O'Neil, Brian J; Sanchez, Leon D; Bruce, Steven E; Pietrzak, Robert H; Joormann, Jutta; Barch, Deanna M; Pizzagalli, Diego A; Smoller, Jordan W; Luna, Beatriz; Harte, Steven E; Elliott, James M; Kessler, Ronald C; Ressler, Kerry J; Koenen, Karestan C; Lyons, Michael S 2022. Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study. PloS one, 17 9, e0273378Westafer, Lauren M; Freiermuth, Caroline E; Lall, Michelle D; Muder, Sarah J; Ragone, Eleanor L; Jarman, Angela F 2022. Experiences of Transgender and Gender Expansive Physicians. JAMA network open, 5 6, e2219791Whiteside, Lauren K; D'Onofrio, Gail; Fiellin, David A; Edelman, E Jennifer; Richardson, Lynne; O'Connor, Patrick; Rothman, Richard E; Cowan, Ethan; Lyons, Michael S; Fockele, Callan E; Saheed, Mustapha; Freiermuth, Caroline; Punches, Brittany E; Guo, Clara; Martel, Shara; Owens, Patricia H; Coupet, Edouard; Hawk, Kathryn F 2022. Models for Implementing Emergency Department-Initiated Buprenorphine With Referral for Ongoing Medication Treatment at Emergency Department Discharge in Diverse Academic Centers. Annals of emergency medicine, 80 5, 410-419Eucker, Stephanie A; Manandhar, Pratik; Arulraja, Kami; Agnihotri, Deepti; Pollack, Charles V; Freiermuth, Caroline 2021. Higher daily pain severity after emergency department visits is associated with lower return-to-work rates. The American journal of emergency medicine, 45 , 48-53Ibemere, Stephanie O; Dubbs, Sarah B; Barnhart, Huiman X; Brown, Jacqueline L; Freiermuth, Caroline E; Kavanagh, Patricia; Paice, Judith A; Strouse, John J; Wilkerson, R Gentry; Tanabe, Paula 2021. Trial design of comparing patient-specific versus weight-based protocols to treat vaso-occlusive episodes in sickle cell disease (COMPARE-VOE). Contemporary clinical trials, 101 , 106252Lane, Bennett H; Lyons, Michael S; Stolz, Uwe; Ancona, Rachel M; Ryan, Richard J; Freiermuth, Caroline E 2021. Naloxone provision to emergency department patients recognized as high-risk for opioid use disorder. The American journal of emergency medicine, 40 , 173-176McCorkle, Maggie L; Kisor, David F; Freiermuth, Caroline E; Sprague, Jon E 2021. Systematic review of Pharmacogenomics Knowledgebase evidence for pharmacogenomic links to the dopamine reward pathway for heroin dependence. Pharmacogenomics, 22 13, 849-857Punches, Brittany E; Ancona, Rachel M; Freiermuth, Caroline E; Brown, Jennifer L; Lyons, Michael S 2021. Incidence of opioid use disorder in the year after discharge from an emergency department encounter. Journal of the American College of Emergency Physicians open, 2 3, e12476Punches, Brittany E; Berger, Kimberly M; Freiermuth, Caroline E; Soliman, Summer A; Walker, Quinn T; Lyons, Michael S 2021. Emergency Nurse Perceptions of Pain and Opioids in the Emergency Department. Pain management nursing : official journal of the American Society of Pain Management Nurses, 22 5, 586-591Punches, Brittany E; Soliman, Summer; Freiermuth, Caroline E; Lane, Bennett H; Lyons, Michael S 2020. Emergency Nurse Perceptions of Naloxone Distribution in the Emergency Department. Journal of emergency nursing, 46 5, 675-681.e1Freiermuth, Caroline E; Lavonas, Eric J; Anderson, Victoria E; Kleinschmidt, Kurt C; Sharma, Kapil; Rapp-Olsson, Malin; Gerardo, Charles 2019. Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation. The western journal of emergency medicine, 20 3, 497-505Fulton, Jessica J; LeBlanc, Thomas W; Cutson, Toni M; Porter Starr, Kathryn N; Kamal, Arif; Ramos, Katherine; Freiermuth, Caroline E; McDuffie, Jennifer R; Kosinski, Andrzej; Adam, Soheir; Nagi, Avishek; Williams, John W 2019. Integrated outpatient palliative care for patients with advanced cancer: A systematic review and meta-analysis. Palliative medicine, 33 2, 123-134Hughes, Jaime M; Freiermuth, Caroline E; Shepherd-Banigan, Megan; Ragsdale, Luna; Eucker, Stephanie A; Goldstein, Karen; Hastings, S Nicole; Rodriguez, Rachel L; Fulton, Jessica; Ramos, Katherine; Tabriz, Amir Alishahi; Gordon, Adelaide M; Gierisch, Jennifer M; Kosinski, Andrzej; Williams, John W 2019. Emergency Department Interventions for Older Adults: A Systematic Review. Journal of the American Geriatrics Society, 67 7, 1516-1525Cline, David M; Silva, Susan; Freiermuth, Caroline E; Thornton, Victoria; Tanabe, Paula 2018. Emergency Department (ED), ED Observation, Day Hospital, and Hospital Admissions for Adults with Sickle Cell Disease. The western journal of emergency medicine, 19 2, 311-318Gunn, Alexander H; Smothers, Zachary P W; Schramm-Sapyta, Nicole; Freiermuth, Caroline E; MacEachern, Mark; Muzyk, Andrew J 2018. The Emergency Department as an Opportunity for Naloxone Distribution. The western journal of emergency medicine, 19 6, 1036-1042Kopec, Kathryn T; Freiermuth, Caroline; Maynard, Susan; Beuhler, Michael 2018. Dinitrophenol (DNP) Fatality Associated with a Falsely Elevated Salicylate Level: a Case Report with Verification of Laboratory Cross Reactivity. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 14 4, 323-326Williams, Hants; Silva, R N Susan; Cline, David; Freiermuth, Caroline; Tanabe, Paula 2018. Social and Behavioral Factors in Sickle Cell Disease: Employment Predicts Decreased Health Care Utilization. Journal of health care for the poor and underserved, 29 2, 814-829Tanabe, Paula; Freiermuth, Caroline E; Cline, David M; Silva, Susan 2017. A Prospective Emergency Department Quality Improvement Project to Improve the Treatment of Vaso-Occlusive Crisis in Sickle Cell Disease: Lessons Learned. Joint Commission journal on quality and patient safety, 43 3, 116-126Freiermuth, Caroline E; Silva, Susan; Cline, David M; Tanabe, Paula 2016. Shift in Emergency Department Provider Attitudes Toward Patients With Sickle Cell Disease. Advanced emergency nursing journal, 38 3, 199-212Dedert, Eric A; McDuffie, Jennifer R; Stein, Roy; McNiel, J Murray; Kosinski, Andrzej S; Freiermuth, Caroline E; Hemminger, Adam; Williams, John W 2015. Electronic Interventions for Alcohol Misuse and Alcohol Use Disorders: A Systematic Review. Annals of internal medicine, 163 3, 205-14Freiermuth, Caroline E; Chandra, Abhinav; Peacock, W Frank 2015. Characteristics of patients that do not initially respond to intravenous antihypertensives in the emergency department: subanalysis of the CLUE trial. The western journal of emergency medicine, 16 2, 276-83Freiermuth, Caroline E; Haywood, Carlton; Silva, Susan; Cline, David M; Kayle, Mariam; Sullivan, Dori; Thornton, Victoria; Tanabe, Paula 2014. Attitudes toward patients with sickle cell disease in a multicenter sample of emergency department providers. Advanced emergency nursing journal, 36 4, 335-47Thornton, Victoria L; Holl, Jane L; Cline, David M; Freiermuth, Caroline E; Sullivan, Dori T; Tanabe, Paula 2014. Application of a proactive risk analysis to emergency department sickle cell care. The western journal of emergency medicine, 15 4, 446-58Blomkalns, Andra L; O'Connell, Elise M; Eady, Caroline E; Lindsell, Christopher J; Gibler, W Brian 2006. Evaluation of dyslipidemia in the emergency department: impact of cholesterol testing on subsequent therapy. American heart journal, 152 6, 1182-6Freiermuth C.E.;Silva S.;Cline D.M.;Tanabe P. 09-01-2016. Shift in Emergency Department Provider Attitudes Toward Patients with Sickle Cell Disease Advanced Emergency Nursing Journal, 38 3, 199-212Williams H.;Silva S.;Cline D.;Freiermuth C.;Tanabe P. 05-01-2018. Social and behavioral factors in sickle cell disease: Employment predicts decreased health care util Journal of Health Care for the Poor and Underserved, 29 2, 814-829Tanabe P.;Freiermuth C.E.;Cline D.M.;Silva S. 03-01-2017. A prospective emergency department quality improvement project to improve the treatment of vaso-occl Joint Commission Journal on Quality and Patient Safety, 43 3, 116-126Fulton J.J.;LeBlanc T.W.;Cutson T.M.;Porter Starr K.N.;Kamal A.;Ramos K.;Freiermuth C.E.;McDuffie J.R.;Kosinski A.;Adam S.;Nagi A.;Williams J.W. 02-01-2019. Integrated outpatient palliative care for patients with advanced cancer: A systematic review and met Palliative Medicine, 33 2, 123-134Freiermuth C.E.;Lavonas E.J.;Anderson V.E.;Kleinschmidt K.C.;Sharma K.;Rapp-Olsson M.;Gerardo C.;Bush S.;Mullins M.;Greene S.;Toschlog E.;Quackenbush E.;Rutherford Rose S.;Schwartz R.;Charlton N.;Lewis B.;Brandehoff N. 01-01-2019. Antivenom Treatment Is Associated with Fewer Patients using Opioids after Copperhead Envenomation Western Journal of Emergency Medicine, 20 3, 497-505Hughes J.M.;Freiermuth C.E.;Shepherd-Banigan M.;Ragsdale L.;Eucker S.A.;Goldstein K.;Hastings S.N.;Rodriguez R.L.;Fulton J.;Ramos K.;Tabriz A.A.;Gordon A.M.;Gierisch J.M.;Kosinski A.;Williams J.W. 01-01-2019. Emergency Department Interventions for Older Adults: A Systematic Review Journal of the American Geriatrics Society, , Thornton V.;Holl J.;Cline D.;Freiermuth C.;Sullivan D.;Tanabe P. 01-01-2014. Application of a proactive risk analysis to emergency department sickle cell care Western Journal of Emergency Medicine, 15 4, 446-458Punches, Brittany E; Ali, Abeer Alhaj; Brown, Jennifer L; Freiermuth, Caroline E; Clark, Angela K; Lyons, Michael S . Opioid-Related Risk Screening Measures for the Emergency Care Setting. Advanced emergency nursing journal, 43 4, 331-343