Education/CredentialsDoctoral Degree: University of MainePostdoctoral Training: Wesleyan University Contact Information Childrens Hospital Bldg R Office 513-636-2705 Email lanyu@ucmail.uc.edu Peer Reviewed Publications Xu, Jingyue; Liu, Han; Park, Joo-Seop; Lan, Yu; Jiang, Rulang 2014. Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis. Development (Cambridge, England), 141 7, 1442-52Zhou, Hao; Zou, Shujuan; Lan, Yu; Fei, Wei; Jiang, Rulang; Hu, Jing 2014. Smad7 modulates TGF? signaling during cranial suture development to maintain suture patency. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 29 3, 716-24Jia, Shihai; Zhou, Jing; Gao, Yang; Baek, Jin-A; Martin, James F; Lan, Yu; Jiang, Rulang 2013. Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development (Cambridge, England), 140 2, 423-32Liu, Han; Lan, Yu; Xu, Jingyue; Chang, Ching-Fang; Brugmann, Samantha A; Jiang, Rulang 2013. Odd-skipped related-1 controls neural crest chondrogenesis during tongue development. Proceedings of the National Academy of Sciences of the United States of America, 110 46, 18555-60Baek, Jin-A; Lan, Yu; Liu, Han; Maltby, Kathleen M; Mishina, Yuji; Jiang, Rulang 2011. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Developmental biology, 350 2, 520-31Gao, Yang; Lan, Yu; Liu, Han; Jiang, Rulang 2011. The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation. Developmental biology, 352 1, 83-91Lan, Yu; Liu, Han; Ovitt, Catherine E; Jiang, Rulang 2011. Generation of Osr1 conditional mutant mice. Genesis (New York, N.Y. : 2000), 49 5, 419-22Zhou, Jing; Gao, Yang; Zhang, Zunyi; Zhang, Yuan; Maltby, Kathleen M; Liu, Zhaoyang; Lan, Yu; Jiang, Rulang 2011. Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field. Developmental biology, 353 2, 344-53Chen, Jianquan; Lan, Yu; Baek, Jin-A; Gao, Yang; Jiang, Rulang 2009. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Developmental biology, 334 1, 174-85Gao, Yang; Lan, Yu; Ovitt, Catherine E; Jiang, Rulang 2009. Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development. Developmental biology, 328 2, 200-9Lan, Yu; Jiang, Rulang 2009. Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth. Development (Cambridge, England), 136 8, 1387-96Liu, Wenjin; Lan, Yu; Pauws, Erwin; Meester-Smoor, Magda A; Stanier, Philip; Zwarthoff, Ellen C; Jiang, Rulang 2008. The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice. Development (Cambridge, England), 135 23, 3959-68Lan, Yu; Wang, Qingru; Ovitt, Catherine E; Jiang, Rulang 2007. A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development. Genesis (New York, N.Y. : 2000), 45 10, 618-24Lan, Yu; Ovitt, Catherine E; Cho, Eui-Sic; Maltby, Kathleen M; Wang, Qingru; Jiang, Rulang 2004. Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development (Cambridge, England), 131 13, 3207-16Lan, Yu; Jia, Shihai; Jiang, Rulang . Molecular patterning of the mammalian dentition. Seminars in cell & developmental biology, 25-26 , 61-70
Peer Reviewed Publications Xu, Jingyue; Liu, Han; Park, Joo-Seop; Lan, Yu; Jiang, Rulang 2014. Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis. Development (Cambridge, England), 141 7, 1442-52Zhou, Hao; Zou, Shujuan; Lan, Yu; Fei, Wei; Jiang, Rulang; Hu, Jing 2014. Smad7 modulates TGF? signaling during cranial suture development to maintain suture patency. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 29 3, 716-24Jia, Shihai; Zhou, Jing; Gao, Yang; Baek, Jin-A; Martin, James F; Lan, Yu; Jiang, Rulang 2013. Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development (Cambridge, England), 140 2, 423-32Liu, Han; Lan, Yu; Xu, Jingyue; Chang, Ching-Fang; Brugmann, Samantha A; Jiang, Rulang 2013. Odd-skipped related-1 controls neural crest chondrogenesis during tongue development. Proceedings of the National Academy of Sciences of the United States of America, 110 46, 18555-60Baek, Jin-A; Lan, Yu; Liu, Han; Maltby, Kathleen M; Mishina, Yuji; Jiang, Rulang 2011. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Developmental biology, 350 2, 520-31Gao, Yang; Lan, Yu; Liu, Han; Jiang, Rulang 2011. The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation. Developmental biology, 352 1, 83-91Lan, Yu; Liu, Han; Ovitt, Catherine E; Jiang, Rulang 2011. Generation of Osr1 conditional mutant mice. Genesis (New York, N.Y. : 2000), 49 5, 419-22Zhou, Jing; Gao, Yang; Zhang, Zunyi; Zhang, Yuan; Maltby, Kathleen M; Liu, Zhaoyang; Lan, Yu; Jiang, Rulang 2011. Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field. Developmental biology, 353 2, 344-53Chen, Jianquan; Lan, Yu; Baek, Jin-A; Gao, Yang; Jiang, Rulang 2009. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Developmental biology, 334 1, 174-85Gao, Yang; Lan, Yu; Ovitt, Catherine E; Jiang, Rulang 2009. Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development. Developmental biology, 328 2, 200-9Lan, Yu; Jiang, Rulang 2009. Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth. Development (Cambridge, England), 136 8, 1387-96Liu, Wenjin; Lan, Yu; Pauws, Erwin; Meester-Smoor, Magda A; Stanier, Philip; Zwarthoff, Ellen C; Jiang, Rulang 2008. The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice. Development (Cambridge, England), 135 23, 3959-68Lan, Yu; Wang, Qingru; Ovitt, Catherine E; Jiang, Rulang 2007. A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development. Genesis (New York, N.Y. : 2000), 45 10, 618-24Lan, Yu; Ovitt, Catherine E; Cho, Eui-Sic; Maltby, Kathleen M; Wang, Qingru; Jiang, Rulang 2004. Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development (Cambridge, England), 131 13, 3207-16Lan, Yu; Jia, Shihai; Jiang, Rulang . Molecular patterning of the mammalian dentition. Seminars in cell & developmental biology, 25-26 , 61-70
Xu, Jingyue; Liu, Han; Park, Joo-Seop; Lan, Yu; Jiang, Rulang 2014. Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis. Development (Cambridge, England), 141 7, 1442-52Zhou, Hao; Zou, Shujuan; Lan, Yu; Fei, Wei; Jiang, Rulang; Hu, Jing 2014. Smad7 modulates TGF? signaling during cranial suture development to maintain suture patency. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 29 3, 716-24Jia, Shihai; Zhou, Jing; Gao, Yang; Baek, Jin-A; Martin, James F; Lan, Yu; Jiang, Rulang 2013. Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development (Cambridge, England), 140 2, 423-32Liu, Han; Lan, Yu; Xu, Jingyue; Chang, Ching-Fang; Brugmann, Samantha A; Jiang, Rulang 2013. Odd-skipped related-1 controls neural crest chondrogenesis during tongue development. Proceedings of the National Academy of Sciences of the United States of America, 110 46, 18555-60Baek, Jin-A; Lan, Yu; Liu, Han; Maltby, Kathleen M; Mishina, Yuji; Jiang, Rulang 2011. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Developmental biology, 350 2, 520-31Gao, Yang; Lan, Yu; Liu, Han; Jiang, Rulang 2011. The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation. Developmental biology, 352 1, 83-91Lan, Yu; Liu, Han; Ovitt, Catherine E; Jiang, Rulang 2011. Generation of Osr1 conditional mutant mice. Genesis (New York, N.Y. : 2000), 49 5, 419-22Zhou, Jing; Gao, Yang; Zhang, Zunyi; Zhang, Yuan; Maltby, Kathleen M; Liu, Zhaoyang; Lan, Yu; Jiang, Rulang 2011. Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field. Developmental biology, 353 2, 344-53Chen, Jianquan; Lan, Yu; Baek, Jin-A; Gao, Yang; Jiang, Rulang 2009. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Developmental biology, 334 1, 174-85Gao, Yang; Lan, Yu; Ovitt, Catherine E; Jiang, Rulang 2009. Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development. Developmental biology, 328 2, 200-9Lan, Yu; Jiang, Rulang 2009. Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth. Development (Cambridge, England), 136 8, 1387-96Liu, Wenjin; Lan, Yu; Pauws, Erwin; Meester-Smoor, Magda A; Stanier, Philip; Zwarthoff, Ellen C; Jiang, Rulang 2008. The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice. Development (Cambridge, England), 135 23, 3959-68Lan, Yu; Wang, Qingru; Ovitt, Catherine E; Jiang, Rulang 2007. A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development. Genesis (New York, N.Y. : 2000), 45 10, 618-24Lan, Yu; Ovitt, Catherine E; Cho, Eui-Sic; Maltby, Kathleen M; Wang, Qingru; Jiang, Rulang 2004. Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development (Cambridge, England), 131 13, 3207-16Lan, Yu; Jia, Shihai; Jiang, Rulang . Molecular patterning of the mammalian dentition. Seminars in cell & developmental biology, 25-26 , 61-70