Education/CredentialsPh.D. : West Virginia University (Pharmaceutical and Pharmacological Sciences)B.S.: Canisius College (Biochemistry) Contact Information Medical Sciences Building 3202 Office 513-558-0333 Email robsonmw@ucmail.uc.edu Research Interests The focus of my laboratory’s research is to understand how traumatic brain injury (TBI) alters neuronal signaling and behavior that is associated with neuropsychiatric disorders including depression and social withdrawal. Chronic changes in psychosocial states, mood and cognition often accompany acute TBI. TBI results in neuroinflammation and molecular signaling alterations within the brain that have been linked to neuropsychiatric disorders, although the precise mechanisms by which th... Peer Reviewed Publications Liu, Xiaoyu; Nemeth, Daniel P; McKim, Daniel B; Zhu, Ling; DiSabato, Damon J; Berdysz, Olimpia; Gorantla, Gowthami; Oliver, Braedan; Witcher, Kristina G; Wang, Yufen; Negray, Christina E; Vegesna, Rekha S; Sheridan, John F; Godbout, Jonathan P; Robson, Matthew J; Blakely, Randy D; Popovich, Phillip G; Bilbo, Staci D; Quan, Ning 2019. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities. Immunity, , Quinlan, Meagan A; Krout, Danielle; Katamish, Rania; Robson, Matthew J; Nettesheim, Catherine; Gresch, Paul J; Mash, Deborah; Henry, Keith; Blakely, Randy D 2019. Human Serotonin Transporter Coding Variation Establishes Conformational Bias with Functional Consequences. ACS chemical neuroscience, , Burke, Susan J; Batdorf, Heidi M; Burk, David H; Martin, Thomas M; Mendoza, Tamra; Stadler, Krisztian; Alami, Wateen; Karlstad, Michael D; Robson, Matthew J; Blakely, Randy D; Mynatt, Randall L; Collier, J Jason 2018. Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet B-cell de-differentiation. Molecular metabolism, , Robson, Matthew J; Quinlan, Meagan A; Margolis, Kara Gross; Gajewski-Kurdziel, Paula A; Veenstra-VanderWeele, Jeremy; Gershon, Michael D; Watterson, D Martin; Blakely, Randy D 2018. p38a MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse. Proceedings of the National Academy of Sciences of the United States of America, , Robson, Matthew J; Quinlan, Meagan A; Blakely, Randy D 2017. Immune System Activation and Depression: Roles of Serotonin in the Central Nervous System and Periphery. ACS chemical neuroscience, 8 5, 932-942Gengo, Fran; Westphal, Erica S; Rainka, Michelle M; Janda, Maria; Robson, Matthew J; Hourihane, J Maurice; Bates, Vernice 2016. Platelet response to increased aspirin dose in patients with persistent platelet aggregation while treated with aspirin 81?mg. Journal of clinical pharmacology, 56 4, 414-21Lucke-Wold, Brandon P; Turner, Ryan C; Logsdon, Aric F; Nguyen, Linda; Bailes, Julian E; Lee, John M; Robson, Matthew J; Omalu, Bennet I; Huber, Jason D; Rosen, Charles L 2016. Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy. Journal of neurosurgery, 124 3, 687-702Robson, Matthew J; Zhu, Chong-Bin; Quinlan, Meagan A; Botschner, David A; Baganz, Nicole L; Lindler, Kathryn M; Thome, Jason G; Hewlett, William A; Blakely, Randy D 2016. Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1. PloS one, 11 3, e0150068Turner, Ryan C; Lucke-Wold, Brandon P; Robson, Matthew J; Lee, John M; Bailes, Julian E 2016. Alzheimer's disease and chronic traumatic encephalopathy: Distinct but possibly overlapping disease entities. Brain injury, 30 11, 1279-1292Baganz, N L; Lindler, K M; Zhu, C B; Smith, J T; Robson, M J; Iwamoto, H; Deneris, E S; Hewlett, W A; Blakely, R D 2015. A requirement of serotonergic p38? mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry, 5 , e671Lucke-Wold, Brandon P; Naser, Zachary J; Logsdon, Aric F; Turner, Ryan C; Smith, Kelly E; Robson, Matthew J; Bailes, Julian E; Lee, John M; Rosen, Charles L; Huber, Jason D 2015. Amelioration of nicotinamide adenine dinucleotide phosphate-oxidase mediated stress reduces cell death after blast-induced traumatic brain injury. Translational research : the journal of laboratory and clinical medicine, 166 6, 509-528.e1Nguyen, Linda; Lucke-Wold, Brandon P; Mookerjee, Shona A; Cavendish, John Z; Robson, Matthew J; Scandinaro, Anna L; Matsumoto, Rae R 2015. Role of sigma-1 receptors in neurodegenerative diseases. Journal of pharmacological sciences, 127 1, 17-29Turner, Ryan C; Lucke-Wold, Brandon P; Logsdon, Aric F; Robson, Matthew J; Dashnaw, Matthew L; Huang, Jason H; Smith, Kelly E; Huber, Jason D; Rosen, Charles L; Petraglia, Anthony L 2015. The Quest to Model Chronic Traumatic Encephalopathy: A Multiple Model and Injury Paradigm Experience. Frontiers in neurology, 6 , 222Turner, Ryan C; Lucke-Wold, Brandon P; Logsdon, Aric F; Robson, Matthew J; Lee, John M; Bailes, Julian E; Dashnaw, Matthew L; Huber, Jason D; Petraglia, Anthony L; Rosen, Charles L 2015. Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery. Frontiers in neurology, 6 , 223Kaushal, Nidhi; Robson, Matthew J; Rosen, Abagail; McCurdy, Christopher R; Matsumoto, Rae R 2014. Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro. European journal of pharmacology, 724 , 193-203Logsdon, Aric Flint; Turner, Ryan Coddington; Lucke-Wold, Brandon Peter; Robson, Matthew James; Naser, Zachary James; Smith, Kelly Elizabeth; Matsumoto, Rae Reiko; Huber, Jason Delwyn; Rosen, Charles Lee 2014. Altering endoplasmic reticulum stress in a model of blast-induced traumatic brain injury controls cellular fate and ameliorates neuropsychiatric symptoms. Frontiers in cellular neuroscience, 8 , 421Matsumoto, Rae R; Nguyen, Linda; Kaushal, Nidhi; Robson, Matthew J 2014. Sigma (?) receptors as potential therapeutic targets to mitigate psychostimulant effects. Advances in pharmacology (San Diego, Calif.), 69 , 323-86Matsumoto, Rae R; Seminerio, Michael J; Turner, Ryan C; Robson, Matthew J; Nguyen, Linda; Miller, Diane B; O'Callaghan, James P 2014. Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia. Pharmacology & therapeutics, 144 1, 28-40Nguyen, Linda; Kaushal, Nidhi; Robson, Matthew J; Matsumoto, Rae R 2014. Sigma receptors as potential therapeutic targets for neuroprotection. European journal of pharmacology, 743 , 42-7Nguyen, Linda; Robson, Matthew J; Healy, Jason R; Scandinaro, Anna L; Matsumoto, Rae R 2014. Involvement of sigma-1 receptors in the antidepressant-like effects of dextromethorphan. PloS one, 9 2, e89985Robson, Matthew J; Turner, Ryan C; Naser, Zachary J; McCurdy, Christopher R; O'Callaghan, James P; Huber, Jason D; Matsumoto, Rae R 2014. SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. Experimental neurology, 254 , 180-9Kaushal, Nidhi; Seminerio, Michael J; Robson, Matthew J; McCurdy, Christopher R; Matsumoto, Rae R 2013. Pharmacological evaluation of SN79, a sigma (?) receptor ligand, against methamphetamine-induced neurotoxicity in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 23 8, 960-71Robson, Matthew J; Seminerio, Michael J; McCurdy, Christopher R; Coop, Andrew; Matsumoto, Rae R 2013. ? Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation. Pharmacological reports : PR, 65 2, 343-9Robson, Matthew J; Turner, Ryan C; Naser, Zachary J; McCurdy, Christopher R; Huber, Jason D; Matsumoto, Rae R 2013. SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation. Experimental neurology, 247 , 134-42Turner, Ryan C; Naser, Zachary J; Logsdon, Aric F; DiPasquale, Kenneth H; Jackson, Garrett J; Robson, Matthew J; Gettens, Robert T T; Matsumoto, Rae R; Huber, Jason D; Rosen, Charles L 2013. Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats. Experimental neurology, 248 , 520-9Kaushal, Nidhi; Elliott, Meenal; Robson, Matthew J; Iyer, Anand Krishnan V; Rojanasakul, Yon; Coop, Andrew; Matsumoto, Rae R 2012. AC927, a ? receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells. Molecular pharmacology, 81 3, 299-308Robson, Matthew J; Elliott, Meenal; Seminerio, Michael J; Matsumoto, Rae R 2012. Evaluation of sigma (?) receptors in the antidepressant-like effects of ketamine in vitro and in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 22 4, 308-17Robson, Matthew J; Noorbakhsh, Bahar; Seminerio, Michael J; Matsumoto, Rae R 2012. Sigma-1 receptors: potential targets for the treatment of substance abuse. Current pharmaceutical design, 18 7, 902-19Seminerio, Michael J; Robson, Matthew J; Abdelazeem, Ahmed H; Mesangeau, Christophe; Jamalapuram, Seshulatha; Avery, Bonnie A; McCurdy, Christopher R; Matsumoto, Rae R 2012. Synthesis and pharmacological characterization of a novel sigma receptor ligand with improved metabolic stability and antagonistic effects against methamphetamine. The AAPS journal, 14 1, 43-51Seminerio, Michael J; Robson, Matthew J; McCurdy, Christopher R; Matsumoto, Rae R 2012. Sigma receptor antagonists attenuate acute methamphetamine-induced hyperthermia by a mechanism independent of IL-1? mRNA expression in the hypothalamus. European journal of pharmacology, 691 1-3, 103-9Turner, Ryan C; Lucke-Wold, Brandon P; Robson, Matthew J; Omalu, Bennet I; Petraglia, Anthony L; Bailes, Julian E 2012. Repetitive traumatic brain injury and development of chronic traumatic encephalopathy: a potential role for biomarkers in diagnosis, prognosis, and treatment? Frontiers in neurology, 3 , 186Xu, Yan-Tong; Robson, Matthew J; Szeszel-Fedorowicz, Wioletta; Patel, Divyen; Rooney, Robert; McCurdy, Christopher R; Matsumoto, Rae R 2012. CM156, a sigma receptor ligand, reverses cocaine-induced place conditioning and transcriptional responses in the brain. Pharmacology, biochemistry, and behavior, 101 1, 174-80Kaushal, Nidhi; Robson, Matthew J; Vinnakota, Harsha; Narayanan, Sanju; Avery, Bonnie A; McCurdy, Christopher R; Matsumoto, Rae R 2011. Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents. The AAPS journal, 13 3, 336-46Fishback, James A; Robson, Matthew J; Xu, Yan-Tong; Matsumoto, Rae R 2010. Sigma receptors: potential targets for a new class of antidepressant drug. Pharmacology & therapeutics, 127 3, 271-82Gengo, Francis M; Rainka, Michelle; Robson, Matthew; Gengo, Michael F; Forrest, Alan; Hourihane, Maurice; Bates, Vernice 2008. Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. Journal of clinical pharmacology, 48 3, 335-43
Research Interests The focus of my laboratory’s research is to understand how traumatic brain injury (TBI) alters neuronal signaling and behavior that is associated with neuropsychiatric disorders including depression and social withdrawal. Chronic changes in psychosocial states, mood and cognition often accompany acute TBI. TBI results in neuroinflammation and molecular signaling alterations within the brain that have been linked to neuropsychiatric disorders, although the precise mechanisms by which th...
Peer Reviewed Publications Liu, Xiaoyu; Nemeth, Daniel P; McKim, Daniel B; Zhu, Ling; DiSabato, Damon J; Berdysz, Olimpia; Gorantla, Gowthami; Oliver, Braedan; Witcher, Kristina G; Wang, Yufen; Negray, Christina E; Vegesna, Rekha S; Sheridan, John F; Godbout, Jonathan P; Robson, Matthew J; Blakely, Randy D; Popovich, Phillip G; Bilbo, Staci D; Quan, Ning 2019. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities. Immunity, , Quinlan, Meagan A; Krout, Danielle; Katamish, Rania; Robson, Matthew J; Nettesheim, Catherine; Gresch, Paul J; Mash, Deborah; Henry, Keith; Blakely, Randy D 2019. Human Serotonin Transporter Coding Variation Establishes Conformational Bias with Functional Consequences. ACS chemical neuroscience, , Burke, Susan J; Batdorf, Heidi M; Burk, David H; Martin, Thomas M; Mendoza, Tamra; Stadler, Krisztian; Alami, Wateen; Karlstad, Michael D; Robson, Matthew J; Blakely, Randy D; Mynatt, Randall L; Collier, J Jason 2018. Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet B-cell de-differentiation. Molecular metabolism, , Robson, Matthew J; Quinlan, Meagan A; Margolis, Kara Gross; Gajewski-Kurdziel, Paula A; Veenstra-VanderWeele, Jeremy; Gershon, Michael D; Watterson, D Martin; Blakely, Randy D 2018. p38a MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse. Proceedings of the National Academy of Sciences of the United States of America, , Robson, Matthew J; Quinlan, Meagan A; Blakely, Randy D 2017. Immune System Activation and Depression: Roles of Serotonin in the Central Nervous System and Periphery. ACS chemical neuroscience, 8 5, 932-942Gengo, Fran; Westphal, Erica S; Rainka, Michelle M; Janda, Maria; Robson, Matthew J; Hourihane, J Maurice; Bates, Vernice 2016. Platelet response to increased aspirin dose in patients with persistent platelet aggregation while treated with aspirin 81?mg. Journal of clinical pharmacology, 56 4, 414-21Lucke-Wold, Brandon P; Turner, Ryan C; Logsdon, Aric F; Nguyen, Linda; Bailes, Julian E; Lee, John M; Robson, Matthew J; Omalu, Bennet I; Huber, Jason D; Rosen, Charles L 2016. Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy. Journal of neurosurgery, 124 3, 687-702Robson, Matthew J; Zhu, Chong-Bin; Quinlan, Meagan A; Botschner, David A; Baganz, Nicole L; Lindler, Kathryn M; Thome, Jason G; Hewlett, William A; Blakely, Randy D 2016. Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1. PloS one, 11 3, e0150068Turner, Ryan C; Lucke-Wold, Brandon P; Robson, Matthew J; Lee, John M; Bailes, Julian E 2016. Alzheimer's disease and chronic traumatic encephalopathy: Distinct but possibly overlapping disease entities. Brain injury, 30 11, 1279-1292Baganz, N L; Lindler, K M; Zhu, C B; Smith, J T; Robson, M J; Iwamoto, H; Deneris, E S; Hewlett, W A; Blakely, R D 2015. A requirement of serotonergic p38? mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry, 5 , e671Lucke-Wold, Brandon P; Naser, Zachary J; Logsdon, Aric F; Turner, Ryan C; Smith, Kelly E; Robson, Matthew J; Bailes, Julian E; Lee, John M; Rosen, Charles L; Huber, Jason D 2015. Amelioration of nicotinamide adenine dinucleotide phosphate-oxidase mediated stress reduces cell death after blast-induced traumatic brain injury. Translational research : the journal of laboratory and clinical medicine, 166 6, 509-528.e1Nguyen, Linda; Lucke-Wold, Brandon P; Mookerjee, Shona A; Cavendish, John Z; Robson, Matthew J; Scandinaro, Anna L; Matsumoto, Rae R 2015. Role of sigma-1 receptors in neurodegenerative diseases. Journal of pharmacological sciences, 127 1, 17-29Turner, Ryan C; Lucke-Wold, Brandon P; Logsdon, Aric F; Robson, Matthew J; Dashnaw, Matthew L; Huang, Jason H; Smith, Kelly E; Huber, Jason D; Rosen, Charles L; Petraglia, Anthony L 2015. The Quest to Model Chronic Traumatic Encephalopathy: A Multiple Model and Injury Paradigm Experience. Frontiers in neurology, 6 , 222Turner, Ryan C; Lucke-Wold, Brandon P; Logsdon, Aric F; Robson, Matthew J; Lee, John M; Bailes, Julian E; Dashnaw, Matthew L; Huber, Jason D; Petraglia, Anthony L; Rosen, Charles L 2015. Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery. Frontiers in neurology, 6 , 223Kaushal, Nidhi; Robson, Matthew J; Rosen, Abagail; McCurdy, Christopher R; Matsumoto, Rae R 2014. Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro. European journal of pharmacology, 724 , 193-203Logsdon, Aric Flint; Turner, Ryan Coddington; Lucke-Wold, Brandon Peter; Robson, Matthew James; Naser, Zachary James; Smith, Kelly Elizabeth; Matsumoto, Rae Reiko; Huber, Jason Delwyn; Rosen, Charles Lee 2014. Altering endoplasmic reticulum stress in a model of blast-induced traumatic brain injury controls cellular fate and ameliorates neuropsychiatric symptoms. Frontiers in cellular neuroscience, 8 , 421Matsumoto, Rae R; Nguyen, Linda; Kaushal, Nidhi; Robson, Matthew J 2014. Sigma (?) receptors as potential therapeutic targets to mitigate psychostimulant effects. Advances in pharmacology (San Diego, Calif.), 69 , 323-86Matsumoto, Rae R; Seminerio, Michael J; Turner, Ryan C; Robson, Matthew J; Nguyen, Linda; Miller, Diane B; O'Callaghan, James P 2014. Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia. Pharmacology & therapeutics, 144 1, 28-40Nguyen, Linda; Kaushal, Nidhi; Robson, Matthew J; Matsumoto, Rae R 2014. Sigma receptors as potential therapeutic targets for neuroprotection. European journal of pharmacology, 743 , 42-7Nguyen, Linda; Robson, Matthew J; Healy, Jason R; Scandinaro, Anna L; Matsumoto, Rae R 2014. Involvement of sigma-1 receptors in the antidepressant-like effects of dextromethorphan. PloS one, 9 2, e89985Robson, Matthew J; Turner, Ryan C; Naser, Zachary J; McCurdy, Christopher R; O'Callaghan, James P; Huber, Jason D; Matsumoto, Rae R 2014. SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. Experimental neurology, 254 , 180-9Kaushal, Nidhi; Seminerio, Michael J; Robson, Matthew J; McCurdy, Christopher R; Matsumoto, Rae R 2013. Pharmacological evaluation of SN79, a sigma (?) receptor ligand, against methamphetamine-induced neurotoxicity in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 23 8, 960-71Robson, Matthew J; Seminerio, Michael J; McCurdy, Christopher R; Coop, Andrew; Matsumoto, Rae R 2013. ? Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation. Pharmacological reports : PR, 65 2, 343-9Robson, Matthew J; Turner, Ryan C; Naser, Zachary J; McCurdy, Christopher R; Huber, Jason D; Matsumoto, Rae R 2013. SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation. Experimental neurology, 247 , 134-42Turner, Ryan C; Naser, Zachary J; Logsdon, Aric F; DiPasquale, Kenneth H; Jackson, Garrett J; Robson, Matthew J; Gettens, Robert T T; Matsumoto, Rae R; Huber, Jason D; Rosen, Charles L 2013. Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats. Experimental neurology, 248 , 520-9Kaushal, Nidhi; Elliott, Meenal; Robson, Matthew J; Iyer, Anand Krishnan V; Rojanasakul, Yon; Coop, Andrew; Matsumoto, Rae R 2012. AC927, a ? receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells. Molecular pharmacology, 81 3, 299-308Robson, Matthew J; Elliott, Meenal; Seminerio, Michael J; Matsumoto, Rae R 2012. Evaluation of sigma (?) receptors in the antidepressant-like effects of ketamine in vitro and in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 22 4, 308-17Robson, Matthew J; Noorbakhsh, Bahar; Seminerio, Michael J; Matsumoto, Rae R 2012. Sigma-1 receptors: potential targets for the treatment of substance abuse. Current pharmaceutical design, 18 7, 902-19Seminerio, Michael J; Robson, Matthew J; Abdelazeem, Ahmed H; Mesangeau, Christophe; Jamalapuram, Seshulatha; Avery, Bonnie A; McCurdy, Christopher R; Matsumoto, Rae R 2012. Synthesis and pharmacological characterization of a novel sigma receptor ligand with improved metabolic stability and antagonistic effects against methamphetamine. The AAPS journal, 14 1, 43-51Seminerio, Michael J; Robson, Matthew J; McCurdy, Christopher R; Matsumoto, Rae R 2012. Sigma receptor antagonists attenuate acute methamphetamine-induced hyperthermia by a mechanism independent of IL-1? mRNA expression in the hypothalamus. European journal of pharmacology, 691 1-3, 103-9Turner, Ryan C; Lucke-Wold, Brandon P; Robson, Matthew J; Omalu, Bennet I; Petraglia, Anthony L; Bailes, Julian E 2012. Repetitive traumatic brain injury and development of chronic traumatic encephalopathy: a potential role for biomarkers in diagnosis, prognosis, and treatment? Frontiers in neurology, 3 , 186Xu, Yan-Tong; Robson, Matthew J; Szeszel-Fedorowicz, Wioletta; Patel, Divyen; Rooney, Robert; McCurdy, Christopher R; Matsumoto, Rae R 2012. CM156, a sigma receptor ligand, reverses cocaine-induced place conditioning and transcriptional responses in the brain. Pharmacology, biochemistry, and behavior, 101 1, 174-80Kaushal, Nidhi; Robson, Matthew J; Vinnakota, Harsha; Narayanan, Sanju; Avery, Bonnie A; McCurdy, Christopher R; Matsumoto, Rae R 2011. Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents. The AAPS journal, 13 3, 336-46Fishback, James A; Robson, Matthew J; Xu, Yan-Tong; Matsumoto, Rae R 2010. Sigma receptors: potential targets for a new class of antidepressant drug. Pharmacology & therapeutics, 127 3, 271-82Gengo, Francis M; Rainka, Michelle; Robson, Matthew; Gengo, Michael F; Forrest, Alan; Hourihane, Maurice; Bates, Vernice 2008. Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. Journal of clinical pharmacology, 48 3, 335-43
Liu, Xiaoyu; Nemeth, Daniel P; McKim, Daniel B; Zhu, Ling; DiSabato, Damon J; Berdysz, Olimpia; Gorantla, Gowthami; Oliver, Braedan; Witcher, Kristina G; Wang, Yufen; Negray, Christina E; Vegesna, Rekha S; Sheridan, John F; Godbout, Jonathan P; Robson, Matthew J; Blakely, Randy D; Popovich, Phillip G; Bilbo, Staci D; Quan, Ning 2019. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities. Immunity, , Quinlan, Meagan A; Krout, Danielle; Katamish, Rania; Robson, Matthew J; Nettesheim, Catherine; Gresch, Paul J; Mash, Deborah; Henry, Keith; Blakely, Randy D 2019. Human Serotonin Transporter Coding Variation Establishes Conformational Bias with Functional Consequences. ACS chemical neuroscience, , Burke, Susan J; Batdorf, Heidi M; Burk, David H; Martin, Thomas M; Mendoza, Tamra; Stadler, Krisztian; Alami, Wateen; Karlstad, Michael D; Robson, Matthew J; Blakely, Randy D; Mynatt, Randall L; Collier, J Jason 2018. Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet B-cell de-differentiation. Molecular metabolism, , Robson, Matthew J; Quinlan, Meagan A; Margolis, Kara Gross; Gajewski-Kurdziel, Paula A; Veenstra-VanderWeele, Jeremy; Gershon, Michael D; Watterson, D Martin; Blakely, Randy D 2018. p38a MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse. Proceedings of the National Academy of Sciences of the United States of America, , Robson, Matthew J; Quinlan, Meagan A; Blakely, Randy D 2017. Immune System Activation and Depression: Roles of Serotonin in the Central Nervous System and Periphery. ACS chemical neuroscience, 8 5, 932-942Gengo, Fran; Westphal, Erica S; Rainka, Michelle M; Janda, Maria; Robson, Matthew J; Hourihane, J Maurice; Bates, Vernice 2016. Platelet response to increased aspirin dose in patients with persistent platelet aggregation while treated with aspirin 81?mg. Journal of clinical pharmacology, 56 4, 414-21Lucke-Wold, Brandon P; Turner, Ryan C; Logsdon, Aric F; Nguyen, Linda; Bailes, Julian E; Lee, John M; Robson, Matthew J; Omalu, Bennet I; Huber, Jason D; Rosen, Charles L 2016. Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy. Journal of neurosurgery, 124 3, 687-702Robson, Matthew J; Zhu, Chong-Bin; Quinlan, Meagan A; Botschner, David A; Baganz, Nicole L; Lindler, Kathryn M; Thome, Jason G; Hewlett, William A; Blakely, Randy D 2016. Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1. PloS one, 11 3, e0150068Turner, Ryan C; Lucke-Wold, Brandon P; Robson, Matthew J; Lee, John M; Bailes, Julian E 2016. Alzheimer's disease and chronic traumatic encephalopathy: Distinct but possibly overlapping disease entities. Brain injury, 30 11, 1279-1292Baganz, N L; Lindler, K M; Zhu, C B; Smith, J T; Robson, M J; Iwamoto, H; Deneris, E S; Hewlett, W A; Blakely, R D 2015. A requirement of serotonergic p38? mitogen-activated protein kinase for peripheral immune system activation of CNS serotonin uptake and serotonin-linked behaviors. Translational psychiatry, 5 , e671Lucke-Wold, Brandon P; Naser, Zachary J; Logsdon, Aric F; Turner, Ryan C; Smith, Kelly E; Robson, Matthew J; Bailes, Julian E; Lee, John M; Rosen, Charles L; Huber, Jason D 2015. Amelioration of nicotinamide adenine dinucleotide phosphate-oxidase mediated stress reduces cell death after blast-induced traumatic brain injury. Translational research : the journal of laboratory and clinical medicine, 166 6, 509-528.e1Nguyen, Linda; Lucke-Wold, Brandon P; Mookerjee, Shona A; Cavendish, John Z; Robson, Matthew J; Scandinaro, Anna L; Matsumoto, Rae R 2015. Role of sigma-1 receptors in neurodegenerative diseases. Journal of pharmacological sciences, 127 1, 17-29Turner, Ryan C; Lucke-Wold, Brandon P; Logsdon, Aric F; Robson, Matthew J; Dashnaw, Matthew L; Huang, Jason H; Smith, Kelly E; Huber, Jason D; Rosen, Charles L; Petraglia, Anthony L 2015. The Quest to Model Chronic Traumatic Encephalopathy: A Multiple Model and Injury Paradigm Experience. Frontiers in neurology, 6 , 222Turner, Ryan C; Lucke-Wold, Brandon P; Logsdon, Aric F; Robson, Matthew J; Lee, John M; Bailes, Julian E; Dashnaw, Matthew L; Huber, Jason D; Petraglia, Anthony L; Rosen, Charles L 2015. Modeling Chronic Traumatic Encephalopathy: The Way Forward for Future Discovery. Frontiers in neurology, 6 , 223Kaushal, Nidhi; Robson, Matthew J; Rosen, Abagail; McCurdy, Christopher R; Matsumoto, Rae R 2014. Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of methamphetamine in vitro. European journal of pharmacology, 724 , 193-203Logsdon, Aric Flint; Turner, Ryan Coddington; Lucke-Wold, Brandon Peter; Robson, Matthew James; Naser, Zachary James; Smith, Kelly Elizabeth; Matsumoto, Rae Reiko; Huber, Jason Delwyn; Rosen, Charles Lee 2014. Altering endoplasmic reticulum stress in a model of blast-induced traumatic brain injury controls cellular fate and ameliorates neuropsychiatric symptoms. Frontiers in cellular neuroscience, 8 , 421Matsumoto, Rae R; Nguyen, Linda; Kaushal, Nidhi; Robson, Matthew J 2014. Sigma (?) receptors as potential therapeutic targets to mitigate psychostimulant effects. Advances in pharmacology (San Diego, Calif.), 69 , 323-86Matsumoto, Rae R; Seminerio, Michael J; Turner, Ryan C; Robson, Matthew J; Nguyen, Linda; Miller, Diane B; O'Callaghan, James P 2014. Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia. Pharmacology & therapeutics, 144 1, 28-40Nguyen, Linda; Kaushal, Nidhi; Robson, Matthew J; Matsumoto, Rae R 2014. Sigma receptors as potential therapeutic targets for neuroprotection. European journal of pharmacology, 743 , 42-7Nguyen, Linda; Robson, Matthew J; Healy, Jason R; Scandinaro, Anna L; Matsumoto, Rae R 2014. Involvement of sigma-1 receptors in the antidepressant-like effects of dextromethorphan. PloS one, 9 2, e89985Robson, Matthew J; Turner, Ryan C; Naser, Zachary J; McCurdy, Christopher R; O'Callaghan, James P; Huber, Jason D; Matsumoto, Rae R 2014. SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. Experimental neurology, 254 , 180-9Kaushal, Nidhi; Seminerio, Michael J; Robson, Matthew J; McCurdy, Christopher R; Matsumoto, Rae R 2013. Pharmacological evaluation of SN79, a sigma (?) receptor ligand, against methamphetamine-induced neurotoxicity in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 23 8, 960-71Robson, Matthew J; Seminerio, Michael J; McCurdy, Christopher R; Coop, Andrew; Matsumoto, Rae R 2013. ? Receptor antagonist attenuation of methamphetamine-induced neurotoxicity is correlated to body temperature modulation. Pharmacological reports : PR, 65 2, 343-9Robson, Matthew J; Turner, Ryan C; Naser, Zachary J; McCurdy, Christopher R; Huber, Jason D; Matsumoto, Rae R 2013. SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation. Experimental neurology, 247 , 134-42Turner, Ryan C; Naser, Zachary J; Logsdon, Aric F; DiPasquale, Kenneth H; Jackson, Garrett J; Robson, Matthew J; Gettens, Robert T T; Matsumoto, Rae R; Huber, Jason D; Rosen, Charles L 2013. Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats. Experimental neurology, 248 , 520-9Kaushal, Nidhi; Elliott, Meenal; Robson, Matthew J; Iyer, Anand Krishnan V; Rojanasakul, Yon; Coop, Andrew; Matsumoto, Rae R 2012. AC927, a ? receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells. Molecular pharmacology, 81 3, 299-308Robson, Matthew J; Elliott, Meenal; Seminerio, Michael J; Matsumoto, Rae R 2012. Evaluation of sigma (?) receptors in the antidepressant-like effects of ketamine in vitro and in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 22 4, 308-17Robson, Matthew J; Noorbakhsh, Bahar; Seminerio, Michael J; Matsumoto, Rae R 2012. Sigma-1 receptors: potential targets for the treatment of substance abuse. Current pharmaceutical design, 18 7, 902-19Seminerio, Michael J; Robson, Matthew J; Abdelazeem, Ahmed H; Mesangeau, Christophe; Jamalapuram, Seshulatha; Avery, Bonnie A; McCurdy, Christopher R; Matsumoto, Rae R 2012. Synthesis and pharmacological characterization of a novel sigma receptor ligand with improved metabolic stability and antagonistic effects against methamphetamine. The AAPS journal, 14 1, 43-51Seminerio, Michael J; Robson, Matthew J; McCurdy, Christopher R; Matsumoto, Rae R 2012. Sigma receptor antagonists attenuate acute methamphetamine-induced hyperthermia by a mechanism independent of IL-1? mRNA expression in the hypothalamus. European journal of pharmacology, 691 1-3, 103-9Turner, Ryan C; Lucke-Wold, Brandon P; Robson, Matthew J; Omalu, Bennet I; Petraglia, Anthony L; Bailes, Julian E 2012. Repetitive traumatic brain injury and development of chronic traumatic encephalopathy: a potential role for biomarkers in diagnosis, prognosis, and treatment? Frontiers in neurology, 3 , 186Xu, Yan-Tong; Robson, Matthew J; Szeszel-Fedorowicz, Wioletta; Patel, Divyen; Rooney, Robert; McCurdy, Christopher R; Matsumoto, Rae R 2012. CM156, a sigma receptor ligand, reverses cocaine-induced place conditioning and transcriptional responses in the brain. Pharmacology, biochemistry, and behavior, 101 1, 174-80Kaushal, Nidhi; Robson, Matthew J; Vinnakota, Harsha; Narayanan, Sanju; Avery, Bonnie A; McCurdy, Christopher R; Matsumoto, Rae R 2011. Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist, in rodents. The AAPS journal, 13 3, 336-46Fishback, James A; Robson, Matthew J; Xu, Yan-Tong; Matsumoto, Rae R 2010. Sigma receptors: potential targets for a new class of antidepressant drug. Pharmacology & therapeutics, 127 3, 271-82Gengo, Francis M; Rainka, Michelle; Robson, Matthew; Gengo, Michael F; Forrest, Alan; Hourihane, Maurice; Bates, Vernice 2008. Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events. Journal of clinical pharmacology, 48 3, 335-43