Czyzyk-Krzeska Laboratory Publications

2025

MacMillan, Austin C; Karki, Bibek; Yang, Juechen; Gertz, Karmela R; Zumwalde, Samantha; Czyzyk-Krzeska, Maria F; Meller, Jarek; Cunningham, John T 2025. PRPS activity tunes redox homeostasis in Myc-driven lymphoma. bioRxiv : the preprint server for biology, ,

2024

Bischoff, Megan E; Shamsaei, Behrouz; Yang, Juechen; Secic, Dina; Vemuri, Bhargav; Reisz, Julie A; D'Alessandro, Angelo; Bartolacci, Caterina; Adamczak, Rafal; Schmidt, Lucas; Wang, Jiang; Martines, Amelia; Biesiada, Jacek; Vest, Katherine E; Scaglioni, Pier P; Plas, David R; Patra, Krushna C; Gulati, Shuchi; Figueroa, Julio A Landero; Meller, Jarek; Cunningham, J Tom; Czyzyk-Krzeska, Maria F 2024. Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma. bioRxiv : the preprint server for biology, ,

Bischoff, Megan E; Shamsaei, Behrouz; Yang, Juechen; Secic, Dina; Vemuri, Bhargav; Reisz, Julie A; D'Alessandro, Angelo; Bartolacci, Caterina; Adamczak, Rafal; Schmidt, Lucas; Wang, Jiang; Martines, Amelia; Venkat, Jahnavi; Toffessi Tcheuyap, Vanina; Biesiada, Jacek; Behrmann, Catherine A; Vest, Katherine E; Brugarolas, James; Scaglioni, Pier Paolo; Plas, David R; Patra, Krushna C; Gulati, Shuchi; Landero Figueroa, Julio A; Meller, Jarek; Cunningham, John T; Czyzyk-Krzeska, Maria F 2024. Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma. Cancer discovery, ,

Thorman, Alexander W; Reigle, James; Chutipongtanate, Somchai; Yang, Juechen; Shamsaei, Behrouz; Pilarczyk, Marcin; Fazel-Najafabadi, Mehdi; Adamczak, Rafal; Kouril, Michal; Bhatnagar, Surbhi; Hummel, Sarah; Niu, Wen; Morrow, Ardythe L; Czyzyk-Krzeska, Maria F; McCullumsmith, Robert; Seibel, William; Nassar, Nicolas; Zheng, Yi; Hildeman, David A; Medvedovic, Mario; Herr, Andrew B; Meller, Jarek 2024. Accelerating drug discovery and repurposing by combining transcriptional signature connectivity with docking. Science advances, 10 35, eadj3010

Behrmann, Catherine A; Ennis, Kelli N; Sarma, Pranjal; Wetzel, Collin; Clark, Nicholas A; Von Handorf, Kate M; Vallabhapurapu, Subrahmanya; Andreani, Cristina; Reigle, James; Scaglioni, Pier Paolo; Meller, Jarek; Czyzyk-Krzeska, Maria F; Kendler, Ady; Qi, Xiaoyang; Sarkaria, Jann N; Medvedovic, Mario; Sengupta, Soma; Dasgupta, Biplab; Plas, David R 2024. Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma. Cancer research communications, 4 8, 2215-2227

2023

Verma, Rita; Aggarwal, Parul; Bischoff, Megan E; Reigle, James; Secic, Dina; Wetzel, Collin; VandenHeuvel, Katherine; Biesiada, Jacek; Ehmer, Birgit; Landero Figueroa, Julio A; Plas, David R; Medvedovic, Mario; Meller, Jarek; Czyzyk-Krzeska, Maria F 2023. Microtubule-associated protein MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells. The Journal of biological chemistry, 299 5, 104663