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This research tests whether acupuncture can reduce pain in people with sickle cell disease and how it affects the brain and blood markers. Participants 14–80 years old who have chronic sickle cell pain are randomly assigned to receive ten sessions (30 minutes each) of either traditional needle acupuncture or non-needle laser acupuncture. The main treatment period includes about 14 in-person visits over roughly 6–8 weeks. Investigators will collect pain and health questionnaires, perform sensory testing before and after treatments, and record brain activity using MRI, fNIRS, and EEG. During imaging, controlled pain stimuli will be applied to the lower leg. Blood samples will be taken before and after the treatment course to study biomarkers, and a noninvasive inner-eyelid image will be used to estimate hemoglobin. Participants will be followed monthly for up to 12 months after the in-person visits to track pain and quality of life. Some procedural details are not provided now to preserve study integrity.
Learn more about this study.
Principal Investigator: Ying Wang, MD, PHD
To Enroll:
This study is exploring whether creating songs and singing together can help breast cancer survivors feel less stressed and more connected to others. Participants will join small group sessions to help design songs or sing them, complete surveys about stress and mood, and wear a heart monitor during some activities. Researchers hope this program will improve emotional well-being and social support.
Principal Investigator: Betsey Z. Nuseibeh, PhD
To Enroll: email nuseibbz@ucmail.uc.edu
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